Evidence map›Paper›PMID 42766203›Full record

ArticleSpine deformity2026

Reoperation and fusion after documented tether breakage following vertebral body tethering: a systematic review and meta-analysis.

Evren Sönmez, Lokman Ayhan, Melih Kapdan

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Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Evren SönmezDepartment of Neurosurgery, University of Health Sciences, Istanbul Kanuni Sultan Süleyman Training and Research Hospital, Atakent Mahallesi, Turgut Özal Bulvarı No:46/1, 34303, Küçükçekmece, Istanbul, Turkey. evren-sonmez@hotmail.com.ORCID http://orcid.org/0000-0002-0457-201X
Lokman AyhanDepartment of Neurosurgery, University of Health Sciences, Istanbul Kanuni Sultan Süleyman Training and Research Hospital, Atakent Mahallesi, Turgut Özal Bulvarı No:46/1, 34303, Küçükçekmece, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-3684-4104
Melih KapdanDepartment of Neurosurgery, University of Health Sciences, Istanbul Kanuni Sultan Süleyman Training and Research Hospital, Atakent Mahallesi, Turgut Özal Bulvarı No:46/1, 34303, Küçükçekmece, Istanbul, Turkey.ORCID http://orcid.org/0009-0003-6415-1414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRadiographic tether breakage after vertebral body tethering (VBT) is common, but its clinical consequence remains uncertain. After a break is detected, the relevant question is not breakage incidence but the conditional probability of further surgery. We quantified patient-level reoperation and fusion-containing surgery after documented breakage.

methodsPubMed/MEDLINE, Scopus, and Web of Science Core Collection were searched from inception through June 30, 2026. Two reviewers independently screened English-language full-text reports, extracted linked post-breakage outcomes, and adjudicated cohort overlap. The primary outcome was any unplanned reoperation after documented breakage; the principal secondary outcome was fusion-containing surgery. One representative cohort per overlap cluster was selected. Proportions were synthesized using a binomial normal generalized linear mixed model.

resultsFive independent cohorts contributed 230 break-positive patients; 41 underwent unplanned reoperation (pooled proportion, 15.7%; 95% CI 6.0-24.4). Four cohorts reported unique fusion-patient counts; 13 of 146 patients underwent fusion-containing surgery (8.9%; 95% CI 3.2-14.2). Thus, 189 of 230 patients (82.2%) had no reported reoperation and 133 of 146 (91.1%) had no reported fusion-containing surgery during source-study follow-up. Certainty was very low for both outcomes.

conclusionDocumented breakage should not be assumed to represent treatment failure or an automatic indication for revision. Most break-positive patients had no reported further surgery during available follow-up in these observational cohorts, although selected patients required tether revision, hybrid salvage, or fusion. Management should be based on interval progression, symptoms, residual deformity, alignment, skeletal maturity, and patient priorities rather than radiographic breakage alone.

Indexed as

Adolescent idiopathic scoliosisMeta-analysisPosterior spinal fusionReoperationTether breakageVertebral body tethering

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.