ArticlePediatric nephrology (Berlin, Germany)2026
Left ventricular remodeling by cardiac magnetic resonance in children with advanced chronic kidney disease: an analysis of the Chronic Kidney Disease in Children (CKiD) study.
Article in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundChildren with advanced chronic kidney disease (CKD) have a high burden of cardiovascular disease (CVD). Left ventricular hypertrophy (LVH) and abnormal myocardial strain are prevalent in CKD patients and confer increased cardiovascular morbidity. While echocardiography is conventionally used to assess myocardial function, cardiovascular magnetic resonance imaging (CMR) provides superior assessment of myocardial morphology and function, including myocardial strain. We conducted an exploratory analysis of the CMR features of children with advanced CKD in the Chronic Kidney Disease in Children (CKiD) study to evaluate the relationship between CKD and CVD severity.
methodsA subset of CKiD patients with eGFR < 30 ml/min/1.73 m
resultsWe analyzed 47 CKiD participants (median age, 16 years; median eGFR, 25 ml/min|1.73 m
conclusionsMyocardial strain > 95th percentile of published normal thresholds on CMR was highly prevalent and related to higher LV mass index in the CKiD cohort with advanced CKD.
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