Evidence map›Paper›PMID 42766074›Full record

ReviewIndian journal of pediatrics2026

Optimising Bone Health in Adolescents: Preventing Poor Bone Accrual and Secondary Osteoporosis.

Anuradha Khadilkar, Vaman Khadilkar, Chirantap Oza, Anaita Hegde, Ripal Shah, Prashant Patil, Suhani Shah, Amulya Ad

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In one paragraph

Review in Indian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anuradha KhadilkarDepartment of Pediatric Endocrinology, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India. anuradhavkhadilkar@gmail.com.ORCID http://orcid.org/0000-0002-3399-3235
Vaman KhadilkarDepartment of Pediatric Endocrinology, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India.
Chirantap OzaDepartment of Pediatric Endocrinology, EndoGrow, Ahmedabad, India.
Anaita HegdeDepartment of Pediatric Neurology, SRCC Narayana Children's Hospital and Jaslok Hospital & Research Centre, Mumbai, India.
Ripal ShahDepartment of Immunohematology and Blood Transfusion, Prathama Blood Centre, Ahmedabad, India.
Prashant PatilDepartment of Pediatric Endocrinology, SRCC Narayana Childrens' Hospital, Mumbai, India.
Suhani ShahDepartment of Pediatric Neurology, SRCC Narayana Children's Hospital and Jaslok Hospital & Research Centre, Mumbai, India.
Amulya AdDepartment of Pediatric Endocrinology, SRCC Narayana Childrens' Hospital, Mumbai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone health during adolescence is influenced by a complex interplay of various factors, disruptions in which may impair bone mineral accrual and predispose to both primary and secondary osteoporosis. Adolescents with chronic medical conditions are at particularly high risk of skeletal deficits. Clinical data from Indian cohorts demonstrate a high burden of low bone mineral density in these populations, with important observations such as the presence of vertebral fractures even in adolescents with BMD Z-scores above -2.0, highlighting the limitations of relying on densitometry alone. Assessment of bone health requires careful interpretation of dual-energy X-ray absorptiometry in the context of growth, with use of size-adjusted measures such as bone mineral apparent density. Vertebral fracture assessment may improve detection of clinically silent skeletal fragility. Optimisation of bone health includes ensuring adequate nutrition, promoting physical activity, and managing underlying disease, with pharmacological therapy considered in selected cases. Early identification and targeted intervention during adolescence provide an opportunity to improve peak bone mass and reduce long-term skeletal morbidity.

Indexed as

Adolescent bone healthBone mineral densityPeak bone massSecondary osteoporosisThalassemiaType 1 diabetes

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.