Evidence map›Paper›PMID 42765918›Full record

ArticleApplied and environmental microbiology2026

A metagenomic survey reveals widespread antibiotic resistance genes in honey bee (

Casey L Gregory, Kevin Radja, David C Haak, Emma L Bradford, Richard D Fell, Jenifer B Walke, Lisa K Belden

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Casey L GregoryDepartment of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0002-9332-0841
Kevin RadjaSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, Virginia, USA.
David C HaakSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0002-3692-3152
Emma L BradfordDepartment of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0002-3591-4748
Richard D FellDepartment of Entomology, Virginia Tech, Blacksburg, Virginia, USA.
Jenifer B WalkeDepartment of Biology, Eastern Washington University, Cheney, Washington, USA.
Lisa K BeldenDepartment of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0002-3514-3920

Funding

Division of Molecular and Cellular Biosciences 1817717Division of Molecular and Cellular Biosciences 1817736
6 · The paper itself

Abstract

Antibiotic use has contributed to antibiotic resistance genes (ARGs) accumulating in many environments, including host-associated microbiomes. Managed honey bee gut bacteria may accumulate ARGs, as honey bees are sometimes treated with antibiotics and often live in agricultural landscapes contaminated with antibiotics. We describe the occurrence and distribution of ARGs in honey bee bacterial gut symbionts from 13 apiaries in a transect across the USA from Washington to Virginia. Using metagenomic sequencing, we detected 55 unique ARGs conferring resistance to 14 classes of antibiotics. Of these, 11 ARGs encoded multidrug resistance. ARGs varied among sites, and ARG composition in hives shifted across the transect. Among honey bee gut bacterial genera, ARG occurrence varied, with

Indexed as

Anti-Bacterial AgentsBacteriaDrug Resistance, BacterialGastrointestinal MicrobiomeGenes, BacterialAnimalsBeesMetagenomicsUnited StatesVirginiaAnti-Bacterial Agentsantibiotic resistanceARGhoney beemicrobiometetracycline

Identifiers

PMID42765918
PMCPMC13689121

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.