Evidence map›Paper›PMID 42765580›Full record

Observational studyJournal of pregnancy2026

Early Adverse Perinatal Outcomes Among Women With Placental Abruption: A Multicenter Prospective Cohort Study in Uganda.

Idiris Omar Siham, Marie Pascaline Sabine Ishimwe, Theodore Nteziyaremye, Rogers Kajabwangu, Ahmed Kiswezi Kazigo, Theoneste Hakizimana

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of pregnancy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Idiris Omar SihamDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda, kiu.ac.ug.
Marie Pascaline Sabine IshimweDepartment of Pediatrics and Child Health, Kampala International University, Ishaka, Uganda, kiu.ac.ug.
Theodore NteziyaremyeDepartment of Sciences, University of Rwanda, Kigali, Rwanda, ur.ac.rw.
Rogers KajabwanguDepartment of Obstetrics and Gynecology, Mbarara University of Science and Technology, Ishaka, Uganda, must.ac.ug.ORCID https://orcid.org/0000-0003-4101-011X
Ahmed Kiswezi KazigoDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda, kiu.ac.ug.
Theoneste HakizimanaDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda, kiu.ac.ug.ORCID https://orcid.org/0000-0002-1294-2981

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPlacental abruption is one of the leading causes of perinatal morbidity and mortality, particularly in low- and middle-income countries. In 2015, the World Health Organization prioritized improving maternal and newborn care to reduce preventable deaths. This study is aimed at determining the proportion of early adverse perinatal outcomes and identifying the factors associated with these outcomes among women with placental abruption delivering at three tertiary hospitals in Uganda.

methodsThis prospective cohort study was conducted from September 30, 2023, to January 30, 2024, at Jinja, Fort Portal, and Mubende Regional Referral Hospitals. A total of 110 consecutive women with clinically diagnosed placental abruption were enrolled in labor suites. Data were collected via pretested questionnaires and analyzed via STATA Version 14.2. Descriptive statistics were used to determine the incidence and describe adverse perinatal outcomes. Associations between variables were assessed using bivariate and multivariate analyses, with a significance level set at p < 0.05 and a 95% confidence interval. The results were presented using pie charts, bar graphs, and tables.

resultsAmong the 110 women with confirmed placental abruption, 70 (63.6%) experienced at least one early adverse perinatal outcome. The most frequent adverse outcomes were neonatal intensive care unit admission (37.1%), stillbirth (27.1%), neonatal death within 48 h (14.3%), low Apgar score (11.4%), and low birth weight (10.0%). Mothers with abnormal fetal heart rates at admission, either abnormally high (adjusted risk ratio [aRR] = 2.80, 95% CI: 1.61-3.22, p = 0.005) or low (aRR = 2.56, 95% CI: 1.50-3.10, p = 0.004), were significantly more likely to experience early adverse perinatal outcomes. Mothers who delivered via spontaneous vaginal delivery were less likely to have adverse outcomes (aRR = 0.335, 95% CI: 0.105-0.923, p = 0.032). Additionally, mothers with > 50% placental detachment were 8 times more likely to experience adverse outcomes (aRR = 2.59, 95% CI: 1.48-3.13, p = 0.005).

conclusionsWomen with placental abruption experienced a high burden of early adverse perinatal outcomes. Abnormal fetal heart rate at admission, mode of delivery, and extent of placental detachment were independently associated with these outcomes. These findings highlight the importance of timely diagnosis, close fetal monitoring, and prompt obstetric management among women presenting with placental abruption.

Indexed as

Abruptio PlacentaePregnancy OutcomeAdultFemaleHumansInfant, NewbornPregnancyProspective StudiesRisk FactorsStillbirthUgandaYoung Adultassociated factorsearly adverse perinatal outcomesincidencemulticenter prospective cohortplacental abruptionUganda

Identifiers

PMID42765580
PMCPMC13591998

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