Trial reportEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2026
Radial wall strain for residual risk stratification after percutaneous coronary intervention.
Trial report in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPercutaneous coronary intervention effectively treats flow-limiting stenoses; however, untreated non-target vessels with vulnerable plaques remain a major contributor to future adverse cardiovascular events. Plaque strain is a promising marker of plaque vulnerability but traditionally requires complex modelling and expensive intracoronary imaging. We developed a novel artificial intelligence algorithm for subpixel-level lumen delineation, enabling real-time automated assessment of radial wall strain (RWS) from routine angiography.
aimsThis post hoc study sought to determine the prognostic value of RWS for predicting future cardiac events in non-target vessels over 5 years, using the high-quality TARGET All Comers randomised trial.
methodsThis blinded analysis included all 1,551 enrolled patients. Angiographic image quality was independently assessed prior to blinded computation of RWS. A prespecified cutoff value of maximal RWS (RWS
resultsRWS was successfully evaluated in 1,384 non-target vessels from 802 patients. Baseline RWS
conclusionsIn this retrospective post hoc analysis, RWS was independently associated with long-term adverse events in deferred non-target vessels, with its prognostic value most evident for subsequent non-target vessel revascularisation. Elevated baseline RWS
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