ArticleJournal of surgical case reports2026
Amniotic membrane allograft for salvage of a complex abdominal wall defect following mesh explantation and wound dehiscence: a case report.
Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Postoperative abdominal wound dehiscence following mesh hernia repair presents a severe surgical challenge. In comorbid elderly patients, definitive abdominal wall reconstruction after mesh explantation carries prohibitive mortality risks. We present a 72-year-old homebound female with a chronic, dehisced midline abdominal wound (17.0 × 2.0 × 1.0 cm) following complicated hernia surgery and subsequent mesh removal at an outside facility. To minimize perioperative risks, a staged, non-reconstructive soft-tissue salvage approach was utilized. The patient underwent two serial operative debridements under monitored anesthesia care and two weeks of continuous negative pressure wound therapy at -125 mmHg. After achieving clean granulation bed over a structurally intact and closed deep fascia, a dehydrated human amniotic membrane allograft (AmnioAMP-MP) was applied. Complete wound closure was achieved within six weeks without secondary mesh reconstruction or complications. Amniotic allografts represent an effective salvage modality for complex abdominal soft-tissue wounds over intact fascial planes.
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