Evidence map›Paper›PMID 42764996›Full record

ReviewActa pharmaceutica Sinica. B2026

Supramolecular strategy in traditional Chinese medicine processing: Mechanistic insights mediated by self-assembly.

Wenqi Song, Huan Gong, Huijun Wang, Doudou Huang, Lianna Sun

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenqi SongSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Huan GongInstitute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Huijun WangInstitute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Doudou HuangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Lianna SunSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The processing of traditional Chinese medicine (TCM) is a critical process that upholds tradition and determines medicinal efficacy. The mechanisms underlying changes in TCM efficacy resulting from processing are currently a key focus of TCM research. Advances in supramolecular chemistry have significantly advanced the understanding of the mechanisms governing the efficacy of TCM complex chemical systems. Both the active ingredient basis and the adjuvant materials used in processing can be regarded as supramolecular units. Processing guides the TCM supermolecules to change structure through covalent forces and self-assemble non-covalently, forming soft matter aggregates that enable selective recognition, transformation, and assembly of components. These aggregates autonomously steer the entire system toward enhanced efficacy and reduced toxicity, thereby revealing the TCM's true active substance foundation. This paper highlights that the dynamic chemical system formed

Indexed as

Covalent chemical reactionsImprint templatesMultidimensional combinationNoncovalent forceProcessingSelf-assemblySoft matter aggregatesSupramolecular

Identifiers

PMID42764996
PMCPMC13589950

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.