Evidence map›Paper›PMID 42764343›Full record

ArticleNature communications2026

Plan-related inequalities in costs, disease progression and mortality among hypertensive patients in China.

Xinghong Guo, Zhiping Guo, Qiuping Zhao, Mingze Ma, Hejia Wan, Nengguang Dai, Tong Jin, Junxing Fan, Tingting Cao, Yanhong Sang and 9 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xinghong Guo *Department of Health Management, College of Public Health, Zhengzhou University, Zhengzhou, China.ORCID http://orcid.org/0009-0008-4488-5054
Zhiping Guo *Henan Key Laboratory of Chronic Disease Health Management, Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University, Zhengzhou, China.
Qiuping Zhao *Henan Provincial Primary Hypertension Management Guidance Center, Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University Zhengzhou, Zhengzhou, China.
Mingze Ma *State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Zhengzhou, China.
Hejia Wan *Henan Provincial Primary Hypertension Management Guidance Center, Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University Zhengzhou, Zhengzhou, China.ORCID http://orcid.org/0009-0003-3900-1967
Nengguang DaiGrassroots Health and Health Department, Health Commission of Henan Province, Zhengzhou, China.
Tong JinGrassroots Health and Health Department, Health Commission of Henan Province, Zhengzhou, China.
Junxing FanHenan Health Personnel Service Center, No.6, Xueli Road, Zhengdong New District, Zhengzhou, Henan, China.
Tingting CaoGrassroots Health and Health Department, Health Commission of Henan Province, Zhengzhou, China.
Yanhong SangDepartment of Endocrinology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yanqing MiaoChina National Health Development Research Center, National Health Commission, Beijing, China.
Yudong MiaoDepartment of Health Management, College of Public Health, Zhengzhou University, Zhengzhou, China.ORCID http://orcid.org/0000-0002-8007-1129
Quanman LiDepartment of Health Management, College of Public Health, Zhengzhou University, Zhengzhou, China.
Yong QiuDepartment of Health Management, College of Public Health, Zhengzhou University, Zhengzhou, China.
ZiWei LiDepartment of Health Management, College of Public Health, Zhengzhou University, Zhengzhou, China.
Jianlin ZhangDepartment of Health Management, College of Public Health, Zhengzhou University, Zhengzhou, China.
Shuaijun GuoCentre for Community Child Health, Murdoch Children's Research Institute, Melbourne, Australia.ORCID http://orcid.org/0000-0001-5737-4765
Jian WuDepartment of Health Management, College of Public Health, Zhengzhou University, Zhengzhou, China. wujian@zzu.edu.cn.
Rongmei LiuHenan Provincial Primary Hypertension Management Guidance Center, Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University Zhengzhou, Zhengzhou, China. liuyongmei0203@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical payment plans shape financial protection and access to care, but their associations with costs, disease progression and survival in hypertension remain poorly characterised. We analyse 8,004,039 inpatient admissions among 4,675,738 patients in Henan, China, from 2019 to 2024 using mixed-effects, multistate and survival models, and externally validate the non-mortality findings in Xinjiang. Compared with self-pay, urban employee, urban-rural resident and commercial or other insurance are associated with 24.95%, 8.71% and 16.64% higher total inpatient expenditure, respectively, while all non-self-pay plans are associated with 89.47-97.56% lower out-of-pocket spending. Urban employee insurance shows the most favourable survival (adjusted hazard ratio for all-cause mortality, 0.72; 95% confidence interval, 0.68-0.76), whereas government-supported or medical assistance arrangements show the poorest survival (1.33; 1.23-1.43) and the greatest expected time in multimorbidity. Sensitivity analyses and external validation support the direction of the main non-mortality findings. These observational associations do not isolate payment-plan effects and may reflect differences in benefit scope, care access and participants' underlying health and social vulnerability. Narrowing reimbursement gaps alone may therefore be insufficient without broader improvements in service coverage and access.

Indexed as

Health Care CostsHypertensionAgedChinaDisease ProgressionFemaleHealth ExpendituresHumansInsurance, HealthMaleMiddle AgedSocioeconomic Disparities in Health

Identifiers

PMID42764343
PMCPMC13590519

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.