Evidence map›Paper›PMID 42764302›Full record

ArticleFunctional & integrative genomics2026

Genome of the tardigrade Cucumibius annulatus: functional annotation and specific proteins.

Daria Makarova, Denis Tumanov, Elena Nassonova, Mikhail Rayko

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Article in Functional & integrative genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Daria MakarovaITMO University, St. Petersburg, Russia.
Denis TumanovDepartment of Invertebrate Zoology, Faculty of Biology, Saint Petersburg State University, St Petersburg, Russia.
Elena NassonovaLaboratory of Cytology of Unicellular Organisms, Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.
Mikhail RaykoITMO University, St. Petersburg, Russia. mike.rayko@gmail.com.ORCID https://orcid.org/0000-0002-3737-1521

Funding

Russian Science Foundation 23-74-00071Russian Science Foundation 25-74-20033
6 · The paper itself

Abstract

Tardigrades are microscopic invertebrates renowned for their capacity to survive extreme environmental conditions, yet stress tolerance strategies vary substantially across the phylum. Here we present the first genome assembly and annotation for the superfamily Isohypsibioidea - the most basal group within the order Parachela - represented by freshwater species Cucumibius annulatus. The draft genome (73 Mb, N50 = 96.4 kb, BUSCO 87.1%) was assembled from short-read data. Orthogroup-based comparison against three reference tardigrades and two ecdysozoan outgroups (Caenorhabditis elegans, Drosophila melanogaster) identified a set of orthogroups unique to C. annulatus. Canonical tardigrade heat-soluble protein families (CAHS, SAHS, MAHS) are present but at lower copy numbers than in other sequenced Parachela, and trehalose biosynthesis enzymes are absent, consistent with the non-anhydrobiotic lifestyle of the species. This study provides a genomic resource for a newly established genus and a comparative framework for interpreting ancestral genomic features of Parachela.

Indexed as

GenomeTardigradaAnimalsGenomicsMolecular Sequence AnnotationPhylogenyComparative genomicsGenomeStress responseTardigrade

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