Evidence map›Paper›PMID 42764157›Full record

ArticleInternational wound journal2026

Full-Body Versus Local Wipe Disinfection With Chlorhexidine Gluconate: No Difference in Surgical Site Infection After Acute Hip Fracture Surgery.

Eila M Sterner, Henrike Häbel, Gunnar V Edman, Wilhelmina Ekström

Abstract readComparative Study
In one paragraph

Article in International wound journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eila M SternerDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-0164-3756
Henrike HäbelDepartment of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden.
Gunnar V EdmanResearch and Development, Norrtälje Hospital, Norrtälje, Sweden.ORCID https://orcid.org/0000-0003-0925-6304
Wilhelmina EkströmDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0009-0005-1012-6699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preoperative skin disinfection is essential to reduce surgical site infection. This study compared full body with local skin disinfection and examined additional patient related factors that could influence surgical site infection. This non-randomized intervention study, conducted over two consecutive periods, included patients with a hip fracture who received preoperative full-body disinfection with 4% chlorhexidine gluconate or local skin disinfection of the hip using 2% chlorhexidine gluconate, with 90 days follow up. Postoperative dressing change was documented. 844 patients were included in the study; 556 (65.7%) patients were treated with full body disinfection and 288 patients (34.1%) with local wipes disinfection. Fourteen patients (1.7%) suffered from a surgical site infection, eleven patients in the full body disinfection group, and three patients with local wipes disinfection without any significant difference found between the groups. Seven (50%) patients with infection had the dressing changed < 48 h. Chronic kidney disease was significantly associated with local infection (p = 0.005). Local preoperative skin disinfection with a washcloth showed no increased risk of wound infection in patients with hip fracture compared to full body disinfection, indicating comparable effectiveness. Impaired kidney function may increase susceptibility. Documentation gaps highlight the need to evaluate adherence to dressing routines to strengthen postoperative wound care. Chlorhexidine gluconate, Full body skin disinfection, Hip fracture, Local wipes disinfection, Surgical site infection.

Indexed as

Anti-Infective Agents, LocalChlorhexidineDisinfectionHip FracturesPreoperative CareSurgical Wound InfectionAgedAged, 80 and overBandagesFemaleHumansMaleMiddle AgedAnti-Infective Agents, LocalChlorhexidinechlorhexidine gluconate

Identifiers

PMID42764157
PMCPMC13590210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.