Evidence map›Paper›PMID 42763924›Full record

ArticleChemistry & biodiversity2026

The Chemical Constituents From Borojo and Their Anti-Inflammatory Activity.

Jinying Ou, Zibin Lu, Lifang Zou, Yuanru Zheng, Xuan Zhao, Xiduan Wei, Linzhong Yu, Huihui Cao, Huhu Zeng, Chunlin Fan and 1 more

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jinying Ou *Third Level Research Laboratory of State Administration of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Zibin Lu *Third Level Research Laboratory of State Administration of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-7174-9420
Lifang Zou *Third Level Research Laboratory of State Administration of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Yuanru ZhengThird Level Research Laboratory of State Administration of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Xuan ZhaoGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou, China.
Xiduan WeiThird Level Research Laboratory of State Administration of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Linzhong YuThird Level Research Laboratory of State Administration of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Huihui CaoThird Level Research Laboratory of State Administration of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-5297-4702
Huhu ZengGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou, China.
Chunlin FanGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou, China.
Junshan LiuThird Level Research Laboratory of State Administration of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-9326-6312

Funding

National Key R&D Program of China 2017YFC1703800Scientific Research Project of Guangdong Provincial Bureau of Traditional Chinese Medicine 20251243the Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme GDHVPS2018Young Elite Scientists Sponsorship Program by CACM 2019-QNRC2-C14
6 · The paper itself

Abstract

Borojo, a fruit native to South America, remains to be comprehensively evaluated for its chemical profile. In this study, we isolated and purified nine compounds from borojo. Among these, three were newly identified cyclopentenes (BLH-1-BLH-3), one was a novel fused-ring compound (BLH-4), and the remaining five were known compounds (BLH-5-BLH-9). To assess their anti-inflammatory potential, we evaluated the compounds in vitro using LPS-stimulated RAW 264.7 murine macrophages. Additionally, we conducted in vivo experiments using zebrafish inflammation models induced by LPS, CuSO

Indexed as

Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalCyclopentanesAnimalsFruitInflammationInterleukin-6LipopolysaccharidesMacrophagesMiceMolecular StructureNF-kappa BRAW 264.7 CellsTumor Necrosis Factor-alphaZebrafishAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalCyclopentanesInterleukin-6LipopolysaccharidesNF-kappa BTumor Necrosis Factor-alphaanti‐inflammationborojocyclopentenesfused ring compoundzebrafish

Identifiers

PMID42763924
PMCPMC13590131

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.