ArticleCurrent health sciences journal
Clinicopathological Features and Statistical Associations in Squamous Cell Carcinoma of the Lip.
Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLip squamous cell carcinoma (SCC) is frequently associated with chronic ultraviolet exposure and actinic cheilitis. Although prognosis is generally favorable, clinicopathological parameters may correlate with tumor characteristics and risk-related patterns. MATERIALS AND
methodsA retrospective study was conducted on 21 cases of lip SCC diagnosed at the County Clinical Emergency Hospital of Craiova between January 2021 and June 2025. Epidemiological and clinical variables (age, sex, area of residence, tumor site and size, macroscopic appearance) and histopathological parameters (subtype, grade, tumor extension, resection margin status, depth of invasion, perineural and vascular invasion) were evaluated. Associations were tested using the Chi-square (χ²) tests in IBM SPSS software.
resultsThe mean age was 74.2±10.88 years, with male predominance (71.4%) and rural residence 71.4% of patients. Most tumors were located on the lower lip (90.4%). Keratinizing SCC was the most frequent histological subtype (61.9%), and well to moderately differentiated tumors (G1-G2) predominated. Muscular invasion was identified in 71.4% of cases, and pT3 was the most frequent (71.4%). Actinic cheilitis was present in all cases. Statistically significant associations were observed between gender and histological grade, tumor site and differentiation, and between histological subtype and degree of differentiation (p<0.05).
conclusionsLip SCC predominantly affects elderly male patients and most frequently involves the lower lip. Tumor localization, depth of invasion, and histological grade showed relevant associations with the aggressiveness of lip SCC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.