ReviewCureus2026
Predictive Value of Respiratory Parameters for Non-invasive Ventilation Failure in Acute Respiratory Failure: A Systematic Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-invasive ventilation (NIV) is first-line therapy in several forms of acute respiratory failure (ARF), but failure is common and delayed intubation carries excess mortality. The best bedside predictors, and when to measure them, are unclear. Following PRISMA 2020, four databases were searched up to 25 June 2026. Peer-reviewed primary studies reporting an association between a respiratory parameter and NIV failure in adults with ARF were eligible. Risk of bias was assessed using the Quality in Prognosis Studies (QUIPS) tool, and a narrative synthesis was performed. Study selection is presented in a PRISMA flow diagram. Twenty studies from 10 countries (~11,700 patient-episodes) covered chronic obstructive pulmonary disease (COPD) exacerbation, de novo hypoxemic failure, pneumonia and acute respiratory distress syndrome (ARDS), including approximately 8,700 hypoxemic and 3,000 hypercapnic episodes. Failure ranged from 13% to 70%, indicating marked heterogeneity. Values before NIV discriminated poorly; those at one to two hours performed well. A partial pressure of arterial oxygen to fraction of inspired oxygen ratio (PaO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.