Evidence map›Paper›PMID 42763292›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2026

Plasmid-encoded Pgp3 protein enhances the infectivity of

Xin Sun, Qi Zhang, Qi Tian, Min Xue, Guangming Zhong, Luying Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin SunDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha 410013, China. w.sunxin@163.com.
Qi ZhangDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Qi TianDepartment of Obstetrics and Gynecology, Affiliated Maternal and Child Health Care Hospital, Hengyang Medical School, University of South China (Hunan Provincial Maternal and Child Health Care Hospital), Changsha 410013, China.
Min XueDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Guangming ZhongDepartment of Microbiology, Immunology and Molecular Genetics, Center at San Antonio, University of Texas Health Science, Texas 78201, USA.
Luying WangDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha 410013, China. 553665449@qq.com.

Funding

the Changsha Natural Science Foundation kq2502203the Natural Science Foundation of Hunan Province 2025JJ70617This is an open access article under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International CC BY-NC-ND 4.0 and //creativecommons.org/licenses/by-nc-nd/4.0/
6 · The paper itself

Abstract

objectivesChlamydial infection can cause a variety of serious diseases, including trachoma, tubal infertility, and rectal lymphogranuloma venereum (LGV). However, the underlying pathogenic mechanisms remain incompletely understood.

methodsFemale C3H/HeJ and CBA/J mice received a subcutaneous injection of medroxyprogesterone acetate 5 days before infection and were subsequently inoculated intravaginally or intrauterinely with 1.0×10

resultsCompared with L2wt, the plasmid-free strain showed significantly reduced chlamydial shedding after intrauterine infection (

conclusions

Indexed as

Antigens, BacterialBacterial ProteinsChlamydia InfectionsChlamydia trachomatisPlasmidsAnimalsFemaleHumansMiceMice, Inbred C3HMice, Inbred CBAAntigens, BacterialBacterial Proteinspgp3 protein, ChlamydiaChlamydia trachomatisinfectivitymouse modelPgp3plasmidserovar L2transformation

Identifiers

PMID42763292
PMCPMC13589763

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.