Evidence map›Paper›PMID 42762475›Full record

ReviewThe American journal of case reports2026

Campylobacter jejuni as a Rare Pathogen in CIED Pocket Infections: A Case Report and Literature Review.

Karolina Barańska-Pawełczak, Bettina Ziaja, Mariusz Opara, Wojciech Jacheć

Abstract readCase ReportsReview
In one paragraph

Review in The American journal of case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karolina Barańska-PawełczakDepartment of Cardiology, Specialist Hospital in Zabrze, Zabrze, Poland.ORCID 0000-0003-4846-5598
Bettina ZiajaDepartment of Cardiology, Specialist Hospital in Zabrze, Zabrze, Poland.
Mariusz OparaDepartment of Cardiology, Specialist Hospital in Zabrze, Zabrze, Poland.
Wojciech JachećSecond Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.ORCID 0000-0002-1091-9788

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Cardiac implantable electronic device (CIED) infections are usually caused by gram-positive bacteria, whereas gram-negative pathogens are uncommon. CASE REPORT We report a case of pacemaker pocket infection caused by Campylobacter jejuni in an immunocompromised patient. The patient underwent uncomplicated dual-chamber pacemaker implantation for sick sinus syndrome. At the first scheduled follow-up, after receiving a diagnosis of primary central nervous system diffuse large B-cell lymphoma and beginning chemotherapy with corticosteroids, swelling and subcutaneous fluid accumulation over the device pocket were observed. There were no local inflammatory signs; the patient had no systemic symptoms or recent history of diarrhea, abdominal pain, nausea, vomiting, or other gastrointestinal symptoms. Inflammatory markers were mildly elevated. Device pocket aspiration yielded straw-colored serous fluid; cultures of pocket fluid and blood grew C. jejuni, prompting a change from empirical amoxicillin-clavulanate to targeted macrolide therapy (intravenous clarithromycin) based on antimicrobial susceptibility testing. Transesophageal echocardiography showed no vegetations on the leads. The entire pacing system (generator and leads) was extracted, and temporary pacing was provided. Inflammatory markers became normalized during continued antibiotic therapy. After clinical stabilization, a new dual-chamber pacemaker was implanted contralaterally. The patient was discharged without signs of persistent infection and remains under regular outpatient follow-up. CONCLUSIONS This case emphasizes that subtle pocket changes in immunocompromised patients may indicate CIED infection, even in the absence of systemic symptoms. The absence of gastrointestinal symptoms suggests silent Campylobacter bacteremia with secondary seeding of the device pocket. Early microbiological sampling, pathogen-directed antimicrobial therapy, and complete device removal remain essential for cure.

Indexed as

Campylobacter InfectionsCampylobacter jejuniPacemaker, ArtificialProsthesis-Related InfectionsAgedAnti-Bacterial AgentsHumansImmunocompromised HostMaleSick Sinus SyndromeAnti-Bacterial Agents

Identifiers

PMID42762475
PMCPMC13599596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.