Evidence map›Paper›PMID 42762392›Full record

ArticleJournal of hematopathology2026

Acute myeloid leukemia arising in treated chronic lymphocytic leukemia/small lymphocytic lymphoma: a challenge in analysis of lineage relationship.

Aruna Rangan, Min Shi, Paul Ollila, Patricia T Greipp, Rong He, David S Viswanatha

Abstract readCase Reports
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In one paragraph

Article in Journal of hematopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aruna RanganDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. rangan.aruna@mayo.edu.ORCID https://orcid.org/0000-0002-5784-5368
Min ShiDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Paul OllilaDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Patricia T GreippDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Rong HeDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
David S ViswanathaDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report a 75-year-old female with a history of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) post obinutuzumab and venetoclax therapy, presenting with CD4+/CD56+/CD123+ acute myeloid leukemia (AML) with histiocytic morphology. The unusual morphology triggered a preliminary diagnosis of CLL transdifferentiation to histiocytic sarcoma (HS); however, a comprehensive workup led to the correct diagnosis of de novo AML. This case showcases the utility of ancillary studies in the work up of secondary myeloid neoplasms post B-cell lymphomas and underlines pitfalls to consider for accurate characterization of these complex malignancies.

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellLeukemia, Myeloid, AcuteNeoplasms, Second PrimaryAgedCell LineageFemaleHumansBlastic plasmacytoid dendritic cell neoplasmCD4+/CD56+/CD123+ acute myeloid leukemiaChronic lymphocytic leukemiaHistiocytic sarcoma

Identifiers

PMID42762392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.