Evidence map›Paper›PMID 42762370›Full record

ReviewFood science of animal resources2026

Slaughter blood-derived bioactive peptides: structure-function relationships, species-specific bioactivities, gastrointestinal stability, and sustainable applications in food systems.

Phanthipha Laosam, Yong Yue, Mahmoud Rouabhia, Saranya Suwanangul, Jukkrapong Pinyo, Sasikan Katemala, Pramote Paengkoum, Chatsirin Nakharuthai, Jaksuma Pongsetkul, Nattapol Pongsamai and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Food science of animal resources, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Phanthipha LaosamResearch and Development Institute, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Yong YueSchool of Animal Technology and Innovation, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Mahmoud RouabhiaOral Ecology Research Group, Faculty of Dentistry, Université Laval, Québec, Canada.
Saranya SuwanangulProgram in Food Science and Technology, Faculty of Engineering and Agro-industry, Maejo University, Chiang Mai, Thailand.
Jukkrapong PinyoFaculty of Agriculture at Kamphaeng Saen, Kasetsart University, Kamphaeng Saen Campus, Nakhon Pathom, Thailand.
Sasikan KatemalaFaculty of Agriculture at Kamphaeng Saen, Kasetsart University, Kamphaeng Saen Campus, Nakhon Pathom, Thailand.
Pramote PaengkoumSchool of Animal Technology and Innovation, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Chatsirin NakharuthaiSchool of Animal Technology and Innovation, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Jaksuma PongsetkulSchool of Animal Technology and Innovation, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Nattapol PongsamaiSuranaree University of Technology Hospital, Nakhon Ratchasima, 30000, Thailand.
Papungkorn SangsawadSchool of Animal Technology and Innovation, Suranaree University of Technology, Nakhon Ratchasima, Thailand. papungkorn@sut.ac.th.

Funding

Full-time Doctoral Researcher FtR.69/9/2569National Science, Research, and Innovation Fund FF3-303-68-12-38(F)
6 · The paper itself

Abstract

This is a comprehensive review focusing on the utilization of slaughter blood proteins as sources of bioactive peptides for functional food applications. Despite significant advances in bioactive peptide research, critical knowledge gaps remain regarding species-specific variations in peptide bioactivity and the complex interplay between processing methods and functional properties. Enzymatic hydrolysis using various proteases generates peptides with diverse bioactivities, including antioxidant, anti-inflammatory, ACE-inhibitory, and DPP-IV inhibitory effects. This review uniquely integrates proteolytic mechanisms with in-depth molecular characterization across multiple animal sources, addressing the previously fragmented understanding of structure-function relationships. Notably, gastrointestinal stability is significantly enhanced by proline residues and hydrophobic amino acids, offering a novel structural insight for predicting peptide bioavailability. Hemoglobin decolorization methods enable broader food industry applications. Recent innovations in processing technologies and delivery systems position blood-derived peptides as valuable functional ingredients for sustainable food systems.

Indexed as

Bioactive peptidesEnzymatic hydrolysisFunctional foodsGastrointestinal stabilitySlaughter blood protein

Identifiers

PMID42762370
PMCPMC13589731

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.