ReviewMethodist DeBakey cardiovascular journal2026
Genetic Causes of Thoracic Aortic Aneurysm: A Review.
Review in Methodist DeBakey cardiovascular journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thoracic aortic aneurysm (TAA) is an important cause of cardiovascular morbidity and mortality. TAA may occur due to inheritable genetic variants affecting the TGFβ signaling cascade, the extracellular matrix, or smooth muscle contraction, which are essential to maintain connective tissue homeostasis and vascular wall integrity. In this review, we summarize the available evidence on the genetics of thoracic aortic aneurysm including known syndromic and non-syndromic hereditary thoracic aortic disorders, the increasingly recognized role of polygenic risk, and the association of TAA with other arteriopathies. We also discuss the evolving role of genetic testing for patients with TAA. A better understanding of genetic predictors for TAA has the potential to improve screening, risk stratification, and the medical and surgical management for this patient population.
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Registered trials
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