ReviewMethodist DeBakey cardiovascular journal2026
Genetic Determinants of Inherited Cardiac Arrhythmias.
Review in Methodist DeBakey cardiovascular journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Inherited cardiac arrhythmias are a major cause of sudden cardiac death in individuals without structural heart disease. These conditions are primarily genetic, resulting from pathogenic variants affecting cardiac ion channels, calcium-handling proteins, intercellular junctions, and transcriptional regulators. While research has traditionally focused on ventricular syndromes such as long QT syndrome, Brugada syndrome, and catecholaminergic polymorphic ventricular tachycardia, atrial fibrillation-particularly early-onset disease-has been increasingly recognized as heritable, especially when affecting young individuals. Advances in molecular genetics have improved diagnosis, risk stratification, and family screening in these diseases as well as the possibility of postmortem evaluation of sudden unexplained death. This review summarizes the genetic basis and clinical implications of these inherited cardiac arrhythmias.
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