Evidence map›Paper›PMID 42761812›Full record

ArticleBaltic journal of health and physical activity2021

Purslane supplementation lowers oxidative stress, inflammatory and muscle damage biomarkers after high-intensity intermittent exercise in female runners.

Anis Charkhi Sahl Abad, Amine Ghram, Rahman Soori, Ali Akbarnejad, Fatemeh Azizi Ghuchan, Mohammad Mehdi Zare, Anthony C Hackney, Stephen J Bailey

Abstract read
In one paragraph

Article in Baltic journal of health and physical activity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Does Multi-Strain Probiotic Supplementation Impact the Effort Capacity of Competitive Road Cyclists?International journal of environmental research and public health · 2022
    Trial
  4. Pharmacologic Mechanisms ofFood science & nutrition · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anis Charkhi Sahl AbadDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
Amine GhramDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
Rahman SooriDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
Ali AkbarnejadDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
Fatemeh Azizi GhuchanDepartment of Exercise Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
Mohammad Mehdi ZareDepartment of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
Anthony C HackneyDepartment of Exercise & Sport Science, University of North Carolina, Chapel Hill, NC, USA.
Stephen J BaileySchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom.

Funding

HEALTH PROMOTION IN CHILDREN--CV RISK FACTORSR01NR001837 · NINR · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI HARRELL, JOANNE S · 1990 to 2004
$2.2M
NINR NIH HHS R01 NR001837
6 · The paper itself

Abstract

Background: The aim of this study was to determine the effect of purslane supplementation on oxidative stress, inflammation and muscle damage biomarkers after completing high-intensity interval exercise (HIIE). Material and methods: Nine healthy female runners completed a HIIE treadmill protocol comprising 1 min at 100% of the peak treadmill velocity attained in a preliminary exhaustive incremental treadmill test, interspersed by 1 min of passive recovery, until they had run for 2.5 km. Athletes repeated this test following 10 days of supplementation with 1000 mg per day of purslane. ‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬. Results: At baseline (i.e., absence of purslane supplementation) the HIIE protocol increased 9-HODE (p < 0.001), 13-HODE (p < 0.001), IL-17 (p < 0.001), TNF-α (p < 0.001), and LDH (p < 0.001). After purslane consumption, resting 9-HODE, 13-HODE, IL-17, TNF-α, and LDH were lowered (p < 0.001) and IL-10 was increased (p < ‬0.001) compared to before purslane supplementation. After purslane consumption and following the HIIE protocol, the responses of these biomarkers were lower compared to baseline (p < 0.001). ‬‬‬‬‬‬‬‬‬‬‬‬‬‬. Conclusions: Ten days of purslane supplementation blunted the perturbation to biomarkers of oxidative stress, inflammation and muscle damage in female runners completing a HIIE protocol.

Indexed as

ergogenic aidexercise biochemistrynutraceuticalrunning exercise

Identifiers

PMID42761812
PMCPMC13587602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.