Epidemiology of adult deceased solid organ donors with positive blood cultures in the USA: a retrospective registry-based study.

Chia-Yu Chiu, Susana Arrigain, Rocio Lopez, Edward Stenehjem, Wendy Armstrong, Jesse D Schold

Abstract read

In one paragraph

Article in Lancet regional health. Americas, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chia-Yu ChiuDivision of Infectious Diseases, Department of Medicine, University of Colorado, Aurora, CO, USA.

Susana ArrigainDivision of Transplant Surgery, Department of Surgery, University of Colorado, Aurora, CO, USA.

Rocio LopezDivision of Transplant Surgery, Department of Surgery, University of Colorado, Aurora, CO, USA.

Edward StenehjemDivision of Infectious Diseases, Department of Medicine, University of Colorado, Aurora, CO, USA.

Wendy ArmstrongDivision of Infectious Diseases, Department of Medicine, University of Colorado, Aurora, CO, USA.

Jesse D ScholdDivision of Transplant Surgery, Department of Surgery, University of Colorado, Aurora, CO, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Organs from donors with positive blood cultures (BCx) have been shown to increase the risk of donor-derived infections. However, the percentage of BCx positivity in donors remains uncertain. Methods: We conducted a retrospective analysis using data from the United Network for Organ Sharing, examining adult donors in the U.S. from 2014 to 2024. Organisms were classified into five mutually exclusive categories: Gram-positive, Gram-negative, anaerobes, suspected contamination, and Findings: Between 2014 and 2024, the percentage of donors with positive BCx increased, rising from 7.0% in 2014 to 13.5% in 2024. The percentage of organisms also increased: Gram-positive (3.8%-6.3%), suspected contaminants (2.9%-6.6%), and Gram-negative (0.84%-1.6%). Donors who were older, male and Black (vs. White) had increased odds of any positive BCx and coagulase-negative Interpretation: This study presents the first national-level epidemiological data on donor blood cultures. Our findings indicate that the percentage of donors with positive BCx has increased over time, and community-acquired bacteremia is associated with donor-related factors. Funding: There was no funding source for this study.

Indexed as

Blood culture contaminationDonor-derived infectionOrgan procurement and transplantation networkStaphylococcus aureusUnited network for organ sharing

Identifiers

PMID42761622

DOI10.1016/j.lana.2026.101638

PMCPMC13586872

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