Evidence map›Paper›PMID 42761574›Full record

ReviewFrontiers in toxicology2026

Organ-specific apoptotic pathways induced by micro- and nanoplastics: a systematic review of

Laura Maria Messina, Maria Concetta Scuto, Gabriella Lupo, Cinzia Maria Grazia Lombardo, Caterina Ledda, Angela Trovato Salinaro

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura Maria Messina *Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Maria Concetta Scuto *Department of Medicine and Surgery, "Kore" University of Enna (UKE), Enna, Italy.
Gabriella LupoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Cinzia Maria Grazia LombardoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Caterina LeddaDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Angela Trovato SalinaroDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread presence of micro- and nanoplastics (MNPs) in environmental matrices and consumer products has raised increasing concern about their potential effects on human health. Due to their small size, persistence, and heterogeneous physicochemical properties, MNPs may interact with biological barriers, reach different cellular compartments, and trigger organ-specific toxic responses. Among the cellular events involved, apoptosis has emerged as a recurrent mechanism linking MNP exposure to tissue injury and functional impairment. This systematic review aimed to synthesize the available

Indexed as

apoptosishuman healthin vitro toxicologymicroplasticsnanoplasticsorgan-specific toxicityoxidative stress

Identifiers

PMID42761574
PMCPMC13586777

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.