ArticleJournal of oral microbiology2026
Supragingival plaque microbiome features in allergic rhinitis and allergic asthma and their association with dental caries: a cross-sectional study.
Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Background: Allergic rhinitis (AR) and allergic asthma (AS) are associated with increased risk of dental caries, potentially associated with alterations in the oral microbiome. Objective: To characterize supragingival plaque microbiome features and their associations with caries severity in allergic adults. Design: This cross-sectional study enrolled patients with cat dander-induced AR or AS, along with age- and sex-comparable normal controls (NC). Supragingival plaque was collected for 16S rRNA gene sequencing. Microbial diversity, ANCOM-BC2 with multiple-testing correction and pseudo-count sensitivity analysis and LEfSe exploratory analysis were performed. Factors of caries severity (DMFT/DMFS) were examined with a random forest model and multivariable negative binomial regression. Results: A total of 89 participants (32 AR, 46 AS and 11 NC) were included. Allergic patients exhibited significantly higher Conclusions: Plaque microbial communities differed across groups, and selected taxa were associated with caries severity among allergic adults. Future investigations are needed to evaluate temporality and mechanisms.
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