Evidence map›Paper›PMID 42761384›Full record

ArticleiScience2026

Perioperative carbohydrate loading improves comfort without adverse metabolic or neonatal effects in gestational diabetes mellitus.

Siqi Liu, Yuxiang Bai, Xiaochang Yang, Longqiong Wang, Hongli Li, Guangmin Song, Ruohan Hu, Tongzhi Wu, Xiaoqing Tan, Qingrong Wu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Siqi LiuDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yuxiang BaiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaochang YangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Longqiong WangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Hongli LiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Guangmin SongDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ruohan HuMedical School, University of Otago, Dunedin, New Zealand.
Tongzhi WuCentre for Research Excellence in Translating Nutritional Sciences to Good Health, School of Medicine, Adelaide University, Adelaide, SA, Australia.
Xiaoqing TanChongqing General Hospital, Chongqing University, Chongqing, China.
Qingrong WuFuling Hospital Affiliated to Chongqing University, Chongqing, China.
Hua ZhangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chang ChenCollege of Pharmacy, Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preoperative carbohydrate loading has been known to overcome discomfort and complications associated with cesarean section, but there is a scarcity of evidence on its safety and benefits in patients with gestational diabetes mellitus (GDM). In this study, pregnant women with normoglycemia and GDM were recruited and grouped according to their nutritional choice prior to cesarean delivery. Blood samples and clinical data were collected, and maternal comfort scores based on self-reports and neonatal data recorded. Metabolomic profiling was performed to explore underlying metabolic responses. Results showed perioperative carbohydrate loading significantly reduced thirst, hunger, and anxiety compared with fasting controls in both the normal and GDM groups. The two groups showed no significant differences at any time point in terms of glycemic measures, inflammatory markers, or maternal and neonatal outcomes. Metabolomic analysis revealed distinct but partially overlapping alterations in metabolic pathways at 1 h before surgery between the two groups.

Indexed as

cesarean sectionenhanced recovery after surgerygestational diabetes mellitusmetabolomicspreoperative loading

Identifiers

PMID42761384
PMCPMC13586518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.