ArticleInternational journal of ophthalmology2026
Evaluation of corneal stromal demarcation line depth after corneal collagen cross-linking with two different UV energy levels in keratoconus: a comparative study using AS-OCT and
Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimTo compare
methodsThis was a retrospective case series. This study included 216 participants (328 eyes) who underwent CXL with either high (7.2 J/cm²) or low (1.8 J/cm²) UV energy. DLD was assessed by IVCM and AS-OCT at 3, 6, and ≥12mo postoperatively. The high-energy group consisted of participants with progressive keratoconus who received CXL treatment, while the low-energy group included participants with refractive errors who underwent femtosecond laser-assisted
resultsThe high-energy group included 111 participants (144 eyes, mean age 23.39±7.30y, 68 males), and low-energy group included 105 participants (184 eyes, mean age 22.95±5.84y, 53 males). At 3 and 6mo, as well as at the final follow-up, visibility of the demarcation line was consistently superior with IVCM compared with AS-OCT (all
conclusionCompared with AS-OCT, IVCM provides clearer and more reliable visualization of the corneal stromal demarcation line after CXL. While both modalities yield comparable depth measurements, IVCM maintains higher visibility across different energy levels and during follow-up at various time points, making it a preferred modality for postoperative assessment in clinical practice.
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