Evidence map›Paper›PMID 42761289›Full record

ArticleOpen forum infectious diseases2026

Perspectives on PrEP/PEP Integration in Telehealth Gender-Affirming Care: A Survey of Clients From a National Telehealth Platform.

Nancy Aitcheson, Yun Li, Yixuan Feng, Caroline S O'Brien, Moira Kyweluk, Nadia Dowshen, Florence Momplaisir

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nancy AitchesonDivision of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-3592-1905
Yun LiDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-8225-4554
Yixuan FengDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Caroline S O'BrienMixed Methods Research Lab, Department of Family Medicine and Community Health, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Moira KywelukThird Space Research, Philadelphia, Pennsylvania, USA.
Nadia DowshenDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-8466-1628
Florence MomplaisirDivision of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-6287-0373

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
NIAID NIH HHS P30 AI045008
6 · The paper itself

Abstract

Background: Transgender individuals face disproportionate HIV burden yet experience significant barriers to accessing biomedical HIV prevention. We assessed awareness, experience, and willingness among trans adults to use pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) when integrated with telehealth-delivered gender-affirming hormone care (GAC). Methods: We conducted a cross-sectional survey of clients receiving GAHC via a national subscription-based telehealth platform between October 2023 and January 2024. Using stratified sampling to ensure inclusion of transgender men (TGM) and those residing in rural areas, we assessed PrEP/PEP awareness, prior use, barriers, and willingness to use these services if recommended by their GAC provider. Multivariable logistic regression identified factors associated with stated willingness (yes/no). Results: Among 387 respondents (from 2506 survey invitations, 15.4% response rate), 54.8% identified as transgender women (TGW), 45% were between the ages of 18 and 25, and 74% identified as white, and 13% resided in rural areas. Pre-exposure prophylaxis awareness was moderate among TGW (56%) and TGM (69%), while PEP awareness was 24% among TGW and 31% among TGM. Only 2% of TGW were using PrEP (0% of TGM), and 0% had used PEP. Despite limited prior utilization, 67% expressed willingness to use PrEP and 66% willingness to use PEP if recommended by their GAC provider. Public insurance (vs private) and self-reported HIV worry (vs not worried) were associated with willingness to use both PrEP (public insurance: aOR 3.64, Conclusions: Among clients of a subscription-based telehealth platform, stated acceptability of integrated PrEP/PEP services was high regardless of gender identity or geography. Limited awareness, cost concerns, and the large gap between awareness and utilization require further attention to realize the potential benefits of biomedical HIV prevention integration into telehealth GAC.

Indexed as

gender-affirming carePEPPrEPtelehealth

Identifiers

PMID42761289
PMCPMC13586756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.