Evidence map›Paper›PMID 42761288›Full record

ArticleFrontiers in cellular and infection microbiology2026

Antibiotic resistance, pathogenicity and genomic characteristics of a novel sequence type 6839

Yafeng Dou, Haochen Wang, Qikai Chen, Bo Zhang, Decheng Wang, Xuan Xia, Feng Fan, Zhihao Wu, Jihong Li

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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yafeng Dou *Department of Pathology, The Second People's Hospital of China Three Gorges University, Yichang, China.
Haochen Wang *College of Medical Science, Three Gorges University, Yichang, China.
Qikai ChenState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University College of Fisheries, Wuhan, China.
Bo ZhangCollege of Medical Science, Three Gorges University, Yichang, China.
Decheng WangCollege of Medical Science, Three Gorges University, Yichang, China.
Xuan XiaCollege of Medical Science, Three Gorges University, Yichang, China.
Feng FanDepartment of Pathology, The Second People's Hospital of China Three Gorges University, Yichang, China.
Zhihao WuState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University College of Fisheries, Wuhan, China.
Jihong LiCollege of Medical Science, Three Gorges University, Yichang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Klebsiella pneumoniae is the most frequently encountered multidrug-resistant bacterial pathogen in humans, but its pathogenic effects on aquatic animals are not well documented. Methods: The ZYRC75 isolate was identified by Gram staining, morphological observations, biochemical assays and 16S rRNA sequencing. Antimicrobial susceptibility testing and artificial infection testing were conducted to determine its resistance phenotype and pathogenicity. The whole genome of the ZYRC75 strain was also sequenced. Results: The isolate ZYRC75 was identified as K. pneumoniae and assigned to ST6839, a novel sequence type. It displayed multidrug resistance against penicillins (carbenicillin, piperacillin, ampicillin, penicillin), chloramphenicol, trimethoprim and tetracycline. Infection experiments confirmed the isolate exhibited significant pathogenicity in bullfrogs. ZYRC75 possessed a single circular chromosome of 5,454,922 bp, carrying 179 virulence‑related genes and 157 antimicrobial‑resistance genes. Discussion: This investigation presents a detailed phenotypic and genomic profile of ZYRC75, revealing its antimicrobial resistance and virulence, and establishing a basis for future studies on the pathogenicity of

Indexed as

Drug Resistance, Multiple, BacterialKlebsiella InfectionsKlebsiella pneumoniaeRana catesbeianaAnimalsAnti-Bacterial AgentsChinaDNA, BacterialGenome, BacterialMicrobial Sensitivity TestsPhylogenyRNA, Ribosomal, 16SSequence Analysis, DNAVirulenceVirulence FactorsWhole Genome SequencingAnti-Bacterial AgentsDNA, BacterialRNA, Ribosomal, 16SVirulence FactorsAmerican bullfrogKlebsiella pneumoniaemultidrug-resistantpathogenicitywhole-genome sequence

Identifiers

PMID42761288
PMCPMC13585994

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.