ArticleOpen forum infectious diseases2026
Contemporary Trends in Candidemia: Mortality, Species, and Antifungal Resistance Across Three Periods (2017-2025) in Houston, Texas.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Methods: In a retrospective cohort study of patients with candidemia in Houston, TX, we compared clinical characteristics, species, and resistance between 3 periods (P1, 2017-2019; P2, 2020-2022; and P3, 2023-2025) and assessed contribution to mortality. We compared 30-day mortality in candidemia versus bacteremia. Results: Among 1275 patients with candidemia (1386 episodes), 30-day mortality increased from P1 to P2 (19.7% vs 31.9%, Conclusions: Increased post-candidemia mortality was associated in part with demographic changes and not with species or resistance changes. Factors underlying the persistent increase in post-candidemia mortality are unclear.
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