Evidence map›Paper›PMID 42761146›Full record

ArticleFrontiers in cardiovascular medicine2026

Exploring the role of ascending aortic length to prevent type A acute aortic dissection.

Alberto Pozzoli, Livia Waltert, Mirko Muretti, Laura Anna Leo, Marta Sannito, N'Guessan Kra, Tiziano Torre, Enrico Ferrari, Susanna Grego, Stefanos Demertzis

Abstract read
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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Alberto Pozzoli *Heart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Livia Waltert *Faculty of Biomedical Sciences, Università Della Svizzera Italiana (USI), Lugano, Switzerland.
Mirko MurettiHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Laura Anna LeoCardiovascular Imaging & Cardiology Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Marta SannitoHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
N'Guessan KraHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Tiziano TorreHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Enrico FerrariHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Susanna GregoFaculty of Biomedical Sciences, Università Della Svizzera Italiana (USI), Lugano, Switzerland.
Stefanos DemertzisHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stanford type A acute aortic dissection (AAD) often occurs before the given threshold for prophylactic surgery. This study investigates the role of the ascending aortic length (AAL) integrated to aortic height index (AHI) as an additional factor in the risk stratification of AAD. Thereby, the relationship between AAL and the aortic diameter, as well as the patient's height, will be evaluated. Methods: Patients undergoing surgery for AAD at our Institution between January 2013 and February 2024 were prospectively collected and retrospectively analysed. The size of the aortic organ was retrospectively measured using computed tomography to define the maximum diameter and the length of the ascending segment by means of syngo.via. The AHI and AHI + length (AHIL) were calculated and compared in all patients. A control group without known aortic pathology had their ascending aorta studied using magnetic resonance imaging, including those with a moderate risk of dissection (AHI >= 2.9 cm/m). Results: During the study period, 119 patients were included. The mean aortic diameter at the time of diagnosis was 5.07 ± 0.6 cm, the mean AAL was 11.94 ± 2.23 cm. In the AHI probability density function, the peak for dissection was 2.94 ± 0.36 cm/m, while for AHIL was 9.8 ± 1.15 cm/m. The difference between the AHI and the AHIL in the risk categorization was highly significant ( Conclusion: The addition of ascending aortic length to the aortic height index provides a potentially useful exploratory morphologic index available to the cardiologic community, helping to discriminate individuals within the moderate risk for acute aortic events. Patients with an AHIL exceeding 9.7 cm/m should be referred to an Aortic Center for a proper multidisciplinary risk evaluation.

Indexed as

acute aortic dissection riskaortic diameter/height indexascending aorta aneurysmascending aortic lengthpreventionrisk-reduction

Identifiers

PMID42761146
PMCPMC13585642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.