Evidence map›Paper›PMID 42761108›Full record

ArticleFrontiers in cardiovascular medicine2026

Long-term outcomes and prognostic factors of hybrid aortic arch repair: a 15-year cohort study.

Guanqing Li, Aijun Chen, Ting Yan, Haisheng Chen, Bin Li, Dongting Ye, Daliang Zhu, Xiaoran Guan, Jianrong Zhou, Xiong Zhang

Abstract read
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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Guanqing Li *Department of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Aijun Chen *Department of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Ting Yan *Department of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Haisheng ChenDepartment of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Bin LiDepartment of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Dongting YeDepartment of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Daliang ZhuDepartment of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Xiaoran GuanDepartment of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Jianrong ZhouPaediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College/National Centre for Cardiovascular Diseases, Beijing, China.
Xiong ZhangDepartment of Cardiovascular Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate long-term outcomes of hybrid aortic arch repair for aortic arch lesions and identify factors associated with late mortality. Methods: We retrospectively enrolled 103 patients with aortic arch lesions who received hybrid aortic arch repair at our center between January 2010 and September 2025. General clinical data, lesion types, surgical methods, perioperative outcomes, and long-term follow-up data were collected. Based on the bypass strategy, patients were divided into an ascending aorta (AA) inflow group ( Results: The mean age was 72.0 ± 10.2 years, and 83.5% were men. Diagnoses included intramural hematoma (40.8%), type B dissection (17.5%), type A dissection (14.6%), arch aneurysm (14.6%), and penetrating ulcer (12.6%). All patients successfully completed the procedure, with no intraoperative or 30-day deaths. During a median follow-up of 75.8 months (IQR, 29-128), procedure-related stroke occurred in 8 patients (7.8%), renal dysfunction in 18 (17.5%), and spinal cord ischemia in none. Eleven patients (10.7%) died, and 8 (7.8%) underwent reintervention, mainly for retrograde type A dissection, endoleak, or new-entry dilation. Survival at 1, 3, 5, and 10 years was 98.0%, 94.6%, 89.0%, and 85.8%; freedom from reintervention was 97.9%, 94.2%, 91.5%, and 89.9%. Cervical debranching was associated with better survival than ascending aortic inflow (log-rank Conclusions: Hybrid aortic arch repair was associated with favorable long-term survival, durable freedom from reintervention, and acceptable neurological outcomes in this single-center cohort. The observed survival advantage in the cervical debranching group should be interpreted cautiously, as ascending aorta inflow was preferentially used in patients with more complex proximal aortic disease. These findings should be considered hypothesis-generating and require validation in larger multicenter studies.

Indexed as

aortic arch lesionsCox regressionhybrid aortic arch repairlong-term outcomessurvival analysisthoracic endovascular aortic repair

Identifiers

PMID42761108
PMCPMC13585604

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