Evidence map›Paper›PMID 42761101›Full record

ArticleFrontiers in medical technology2026

Independent testing infrastructure for new approach methodologies: the UC Davis NAMs testing center.

K C Kent Lloyd

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medical technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

K C Kent LloydDepartment of Surgery, School of Medicine and Mouse Biology Program, University of California, Davis, CA, United States.

Funding

KOMP2-Phase3 Production and Phenotyping by the DTCC Consortium TCP Transfer to UC DavisUM1OD023221 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2016 to 2026
$45.7M
UCD Mutant Mouse Regional Resource CenterU42OD012210 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2012 to 2026
$29.2M
MMRRC Informatics, Coordination, and Service Center at UC DavisU42OD010983 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2012 to 2026
$12.9M
The National Center for Metabolic Phenotyping of Mouse Models of Obesity and Diabetes (MPMOD) at UC DavisU2CDK135074 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Jill Lynn Silverman · 2023 to 2026
$4.0M
NIDDK NIH HHS U2C DK135074NIH HHS U42 OD010983NIH HHS U42 OD012210NIH HHS UM1 OD023221
6 · The paper itself

Abstract

As biomedical research moves toward greater use of human-based experimental systems, the practical problem is no longer simply how to develop new models, but how to determine when they are valid and predictable for a particular use. Independent testing infrastructure can help make that determination. The UC Davis NAMs Testing Center is one model for bringing comparative biology, engineering, clinical and computational expertise together to evaluate NAMs for defined biomedical research purposes.

Indexed as

biomedical researchcontext of usenew approach methodologiesreproducibilitytranslational modelsvalidationverification

Identifiers

PMID42761101
PMCPMC13585975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.