ArticleFrontiers in surgery2026
Acute appendicitis before, during, and after the COVID-19 pandemic: a population-based cohort study.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background: Acute appendicitis remains a common surgical emergency. The COVID-19 pandemic severely impacted all the health systems globally including surgical emergencies management. This study aimed to assess changes in diagnosis and treatment of acute appendicitis in a tertiary emergency hospital serving an urban population before, during, and after the COVID-19 years. Methods: This was a population-based cohort study including consecutive ≥ 18-year-old residents of a metropolitan area presenting with acute appendicitis at the tertiary emergency hospital. The study period between January 2018 and December 2023 was divided into: 2018-2019 (pre-COVID-19); 2020-2021 (COVID-19); 2022-2023 (post-COVID-19). Comparisons among the three periods were performed using one-way ANOVA and the Chi-square or Fisher's exact test as appropriate. Results: The breakdown of 1,721 patients included was: 662 in 2018-2019, 422 in 2020-2021, and 637 in 2022-2023. Although the catchment area population (1,817 vs. 1,799 vs. 1,781 MM; Conclusions: This six-year population-based study found a decreased number of patients presenting with acute appendicitis during the pandemic years, with a relative increase in complicated cases but no difference in mortality rates. The rates of appendiceal neoplasms raise concerns regarding the offering of conservative treatment.
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