Evidence map›Paper›PMID 42761078›Full record

ArticleFrontiers in medicine2026

Machine learning-based risk prediction model for postoperative abdominal distension after spinal surgery under general anesthesia.

Chanli Wu, Liju Xie, Shihao Zhou, Yingjie Hu, Xialin Li, Zheng Huang, Dazhi Yang, Xihong Mou

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chanli Wu *Department of Orthopaedics, Shenzhen Nanshan People's Hospital, Shenzhen, China.
Liju Xie *Department of Orthopaedics, Shenzhen Nanshan People's Hospital, Shenzhen, China.
Shihao Zhou *Graduate School, Qinghai University, Xining, China.
Yingjie HuDepartment of Orthopaedics, Shenzhen Nanshan People's Hospital, Shenzhen, China.
Xialin LiDepartment of Orthopaedics, Affiliated Nanshan Hospital of Shenzhen University, Shenzhen, China.
Zheng HuangDepartment of Orthopaedics, Affiliated Nanshan Hospital of Shenzhen University, Shenzhen, China.
Dazhi YangDepartment of Orthopaedics, Affiliated Nanshan Hospital of Shenzhen University, Shenzhen, China.
Xihong MouDepartment of Orthopaedics, Shenzhen Nanshan People's Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early identification of patients at risk of postoperative abdominal distension after spinal surgery remains clinically difficult. Machine learning may improve risk prediction by integrating routinely available perioperative information. Objective: This study aimed to develop and internally validate an interpretable machine learning-based predictive model for postoperative abdominal distension after spinal surgery under general anesthesia and to identify clinically relevant predictors for early nursing risk stratification. Methods: This retrospective single-center prediction model study included 1,234 patients who underwent spinal surgery under general anesthesia. Seventeen routinely recorded perioperative and early postoperative variables were evaluated, including postoperative ADL category(ADL), PCA, and postoperative antibiotic use (yes/no). The data were split using stratified sampling into training (80%) and internal test (20%) sets. Missing-value imputation, scaling, five-fold cross-validated grid search, and model fitting were performed within the training workflow. Logistic regression(LR), RF, support vector machine(SVM), and gradient boosting (GB)models were evaluated using discrimination, calibration, Brier score, decision curve analysis, and permutation importance. Exact TreeSHAP analysis was used to interpret global and patient-specific contributions in the highest-AUC model. Results: Postoperative abdominal distension occurred in 138 of 1,234 patients (11.18%). In the internal test set ( Conclusion: The models showed moderate internal discrimination but materially different sensitivity-specificity trade-offs. Permutation importance and TreeSHAP consistently identified PCA and drainage tube placement as leading random-forest predictors, while TreeSHAP additionally showed the direction and patient-specific magnitude of each contribution. These model explanations are predictive rather than causal. Prospective temporal validation, external validation, and threshold selection are required before bedside use.

Indexed as

abdominal distensiongeneral anesthesiamachine learningrisk predictionspinal surgery

Identifiers

PMID42761078
PMCPMC13585623

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.