ArticleFrontiers in medicine2026
An evaluation of the relationship between BIS and MOAA/S during remimazolam-sufentanil induction: a prospective observational study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Both the Bispectral Index (BIS) and the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale are commonly used to evaluate the depth of anesthesia in studies investigating the effective dosing of remimazolam. However, their correlation remains unclear. This prospective observational study aimed to characterize the correlation between BIS values and MOAA/S scores during induction of anesthesia with remimazolam-sufentanil in elderly and non-elderly patients. Methods: Sixty patients were enrolled and stratified into elderly and non-elderly cohorts ( Results: The correlation between BIS and MOAA/S showed a dynamic pattern, demonstrating a moderate association at the initiation of induction (T1; Conclusion: Bispectral Index and MOAA/S exhibit a complex non-linear relationship and slight concordance during induction with remimazolam-sufentanil.
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