Evidence map›Paper›PMID 42761004›Full record

Trial reportFrontiers in neurology2026

Clinical efficacy and cortical network modulation of a multimodal sensory feedback upper-limb rehabilitation robot for post-stroke upper-limb recovery: a randomized controlled trial.

Li-Hui Zhao, Jun-Peng Zhang, Jia-Jia Wu, Yu Cao, Zhan-Yue Lu, Xu-Yun Hua, Xia Bi, Jian-Guang Xu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li-Hui Zhao *School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jun-Peng Zhang *School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jia-Jia WuEngineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation, Ministry of Education, Shanghai, China.
Yu CaoDepartment of Rehabilitation Medicine, Zhoupu Hospital, Shanghai, China.
Zhan-Yue LuDepartment of Rehabilitation Medicine, Zhoupu Hospital, Shanghai, China.
Xu-Yun HuaEngineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation, Ministry of Education, Shanghai, China.
Xia BiDepartment of Rehabilitation Medicine, Zhoupu Hospital, Shanghai, China.
Jian-Guang XuSchool of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recovery of upper-limb motor function after stroke often requires intensive, repetitive, task-oriented rehabilitation. Multimodal sensory-feedback robot-assisted training has the potential to enhance patient engagement and sensorimotor integration, and thereby improve rehabilitation outcomes. Aim: To investigate the clinical and neurophysiological effects of adding multimodal sensory-feedback robot-assisted training to conventional rehabilitation for post-stroke upper-limb recovery using functional near-infrared spectroscopy (fNIRS). Methods: A total of 38 stroke patients were randomly assigned to a control group (conventional rehabilitation, Results: No significant between-group difference in FMA-UE was observed at baseline ( Conclusion: Adding multimodal sensory-feedback robot-assisted training to dose-matched conventional rehabilitation may improve short-term post-stroke upper-limb motor recovery. fNIRS further revealed intervention-related changes in cortical activation and resting-state functional connectivity. Clinical trial registration: Identifier, ChiCTR2400080101.

Indexed as

Cerebral CortexFeedback, SensoryNerve NetRecovery of FunctionRoboticsStrokeStroke RehabilitationUpper ExtremityAdultAgedFemaleHumansMaleMiddle AgedSpectroscopy, Near-InfraredTreatment Outcomecortical activationfNIRSfunctional connectivitymultimodal sensory feedbackneuroplasticityrobot-assisted therapystrokeupper-limb rehabilitation

Identifiers

PMID42761004
PMCPMC13585541

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.