Evidence map›Paper›PMID 42760538›Full record

ArticleInjury epidemiology2026

Temporal trends in leading causes of injury deaths in Canada from 2000 to 2023: a time series analysis of mortality data.

Xiaoquan Yao, Steven R McFaull, Gisèle Contreras, Wendy Thompson

Abstract read
In one paragraph

Article in Injury epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoquan YaoCentre for Surveillance and Applied Research, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, 785 Carling Avenue, Ottawa, ON, K1A 0K9, Canada. xiaoquan.yao@phac-aspc.gc.ca.ORCID https://orcid.org/0009-0006-3679-6567
Steven R McFaullCentre for Surveillance and Applied Research, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, 785 Carling Avenue, Ottawa, ON, K1A 0K9, Canada.
Gisèle ContrerasCentre for Surveillance and Applied Research, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, 785 Carling Avenue, Ottawa, ON, K1A 0K9, Canada.
Wendy ThompsonCentre for Surveillance and Applied Research, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, 785 Carling Avenue, Ottawa, ON, K1A 0K9, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding long-term trends in causes of injury mortality is essential for informing prevention strategies and public health priorities. In Canada, most studies focused on individual causes of injury deaths, with limited examination of how leading causes evolved collectively over time. This study aimed to assess trends in leading causes of injury mortality and changes in the rankings of leading causes in Canada from 2000 to 2023, overall and by sex and age group.

methodsMortality data were obtained from the Canadian Vital Statistics - Death database, Canadian Coroner and Medical Examiner Database and provincial/territorial chief coroner or chief medical examiner offices. Leading causes of injury deaths were ranked based on their annual crude mortality rates. A joinpoint regression model was applied to quantify trends by annual percent change of age-standardized or crude mortality rates for each leading cause with stratification by sex and age group.

resultsFalls, poisonings, suicide and land transport incidents were consistently the top four leading causes of injury deaths for both males and females during the study period, although their relative rankings and trends varied by sex. Age groups had different leading cause rankings and trends. Overall, age-standardized mortality rate (ASMR) increased annually for poisonings (9.2%) and falls (4.6%), while ASMR for land transport incidents had an annual decline of 3.1%. ASMR also decreased annually for struck by/against (2.1%), smoke/fire/flame (2.0%), homicide (1.7%) and drowning (0.8%). Compared with males, females experienced a faster increase in fall-related mortality and a steeper decline in land transport incident-related deaths. Females had an annual increase of 0.8% in the suicide ASMR. Crude mortality rate for poisonings increased annually among 10-79-years-olds (6.5%-9.3%), while fall-related mortality increased among those 45 years and older (1.7%-5.7% annually) but declined among those under 45 years (1.1%-4.8% annually).

conclusionsThe profile of injury mortality in Canada has shifted over the past two decades, highlighting the need for targeted injury prevention strategies that address the growing burden of falls and poisonings while sustaining progress in declining causes. Continuous data collection and research are important for injury surveillance and prevention.

Indexed as

CanadaFallsInjuriesLand transport incidentsLeading causesMortalityPoisoningsSuicideTrend analysisUnintentional injuries

Identifiers

PMID42760538
PMCPMC13587287

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.