Evidence map›Paper›PMID 42760536›Full record

ArticleActa neuropathologica communications2026

Neuro-glial lipid imbalance in a Drosophila model of amyotrophic lateral sclerosis 8.

Lovleen Garg, Kriti Chaplot, Gowhith Kuppili, Shweta Tendulkar, Jomon Joseph, Siddhesh Kamat, Girish Ratnaparkhi

Abstract read
In one paragraph

Article in Acta neuropathologica communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lovleen GargDepartment of Biology, Indian Institute of Science Education and Research (IISER), Dr Homi Bhabha Road, Pashan, Pune, 411008, India.ORCID http://orcid.org/0000-0003-3592-0440
Kriti ChaplotDepartment of Biology, Indian Institute of Science Education and Research (IISER), Dr Homi Bhabha Road, Pashan, Pune, 411008, India.ORCID http://orcid.org/0000-0002-8939-4696
Gowhith KuppiliBiotechnology Research and Innovation Council - National Centre for Cell Science (BRIC-NCCS), Savitribai Phule Pune University Campus, Ganeshkhind Road, Pune, 411007, India.ORCID http://orcid.org/0009-0003-1502-2771
Shweta TendulkarDepartment of Biology, Indian Institute of Science Education and Research (IISER), Dr Homi Bhabha Road, Pashan, Pune, 411008, India.ORCID http://orcid.org/0000-0001-9305-7169
Jomon JosephBiotechnology Research and Innovation Council - National Centre for Cell Science (BRIC-NCCS), Savitribai Phule Pune University Campus, Ganeshkhind Road, Pune, 411007, India.ORCID http://orcid.org/0000-0002-3042-6286
Siddhesh KamatDepartment of Biology, Indian Institute of Science Education and Research (IISER), Dr Homi Bhabha Road, Pashan, Pune, 411008, India.ORCID http://orcid.org/0000-0001-6132-7574
Girish RatnaparkhiDepartment of Biology, Indian Institute of Science Education and Research (IISER), Dr Homi Bhabha Road, Pashan, Pune, 411008, India. girish@iiserpune.ac.in.ORCID http://orcid.org/0000-0001-7615-3140

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
ANRF, India SB/SJF/2021-22/01EMSTAR SL03NIH HHS P40 OD018537
6 · The paper itself

Abstract

Membrane Contact sites (MCS) have emerged as physiologically relevant zones that coordinate inter-organelle communication and cellular function. VAPB, an ER-resident MCS tethering protein, plays a central role in regulating MCSs through its numerous protein interactors, thereby influencing cellular homeostasis. A pathogenic missense VAPB

Indexed as

Amyotrophic Lateral SclerosisBrainLipid MetabolismNeurogliaAnimalsAnimals, Genetically ModifiedDisease Models, AnimalDrosophilaDrosophila ProteinsHumansVesicular Transport ProteinsDrosophila ProteinsVAPB protein, humanVesicular Transport ProteinsCholesterolClimbingGliaLipid dropletsNeurodegenerationVAP33A

Identifiers

PMID42760536
PMCPMC13587292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.