Evidence map›Paper›PMID 42760519›Full record

ArticleBMC infectious diseases2026

Helcococcus kunzii as a rare etiological agent of spondylodiscitis partially managed with oral antibiotic therapy in a patient with diabetes mellitus: a case report.

Karen Velázquez-Leonel, Christian Bepperling, Thomas Regnath, Farzam Vazifehdan, Edgar Santos

Abstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karen Velázquez-LeonelSpine Center Stuttgart, Paulinenhilfe, Diakonie-Klinikum Stuttgart, Rosenbergstraße 38, 70176, Stuttgart, Germany. karen.velazquez-leonel@uni-oldenburg.de.
Christian BepperlingSpine Center Stuttgart, Paulinenhilfe, Diakonie-Klinikum Stuttgart, Rosenbergstraße 38, 70176, Stuttgart, Germany.
Thomas RegnathLaboratory Prof. G. Enders and colleagues, Rosenbergstraße 85, 70193, Stuttgart, Germany.
Farzam VazifehdanSpine Center Stuttgart, Paulinenhilfe, Diakonie-Klinikum Stuttgart, Rosenbergstraße 38, 70176, Stuttgart, Germany.
Edgar SantosSpine Center Stuttgart, Paulinenhilfe, Diakonie-Klinikum Stuttgart, Rosenbergstraße 38, 70176, Stuttgart, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have reported Helcococcus kunzii infection in a range of clinical conditions, including infective endocarditis, umbilical abscesses, bacteremia, diabetic foot infections, and prosthetic joint infections. Diabetes mellitus has been identified as a predisposing condition for infections caused by this pathogen. We report the first documented case of spondylodiscitis caused by Helcococcus kunzii. CASE PRESENTATION: We describe a case of spondylodiscitis caused by Helcococcus kunzii in a 62-year-old man with long-standing type 1 diabetes mellitus who presented to the emergency department with severe, immobilizing lumbar pain. Clinical diagnosis of spondylodiscitis was established by magnetic resonance imaging (MRI). Helcococcus kunzii was isolated from four separate blood culture sets. During surgical intervention, two swabs and two tissue samples were collected. H. kunzii was identified in all specimens using MALDI-TOF mass spectrometry (MALDI-TOF MS) with log scores ranging from 2.30 to 2.52. The patient received intravenous β-lactam antibiotics for ten days, followed by 13 weeks of oral β-lactam antibiotics. Follow-up MRI performed before discharge showed no further evidence of spondylodiscitis. At the 3-month follow-up visit, the patient demonstrated clinical improvement.

conclusionsThis case demonstrates that H. kunzii should be considered a potential etiological agent of pyogenic spondylodiscitis, particularly in patients with diabetes mellitus and associated comorbidities that may compromise skin barrier integrity. MALDI-TOF MS is essential for accurate identification of this organism and should be considered in cases of atypical spondylodiscitis.

Indexed as

Anti-Bacterial AgentsDiabetes Mellitus, Type 1DiscitisGram-Positive Bacterial InfectionsAdministration, OralDiabetes ComplicationsHumansMagnetic Resonance ImagingMaleMiddle AgedSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAnti-Bacterial AgentsCase reportDiabetes mellitusHelcococcus kunziiMALDI-TOF MSSpondylodiscitis

Identifiers

PMID42760519
PMCPMC13589352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.