Evidence map›Paper›PMID 42760362›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Rapid eye movement-related obstructive sleep apnea: a physiological phenotype predicting favorable outcomes following palatal surgery.

Ya-Wei Hsiao, Chun-Ting Lu, Li-Ang Lee, Ming-Shao Tsai, Li-Pang Chuang, Wan-Ni Lin, Li-Jen Hsin, Yi-Chieh Lee, Tuan-Jen Fang, Hsueh-Yu Li

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ya-Wei HsiaoDepartment of Otorhinolaryngology, Head and Neck Surgery, Sleep Center, Linkou Medical Center, Chang Gung Memorial Hospital, No. 5, Fu-Hsing Street, Gueishan District, Taoyuan City, 33305, Taiwan.ORCID http://orcid.org/0000-0003-3783-6699
Chun-Ting LuDepartment of Otorhinolaryngology - Head and Neck Surgery, New Taipei Municipal Tucheng Hospital, New Taipei City, Taiwan.ORCID http://orcid.org/0000-0002-0959-9393
Li-Ang LeeDepartment of Otorhinolaryngology, Head and Neck Surgery, Sleep Center, Linkou Medical Center, Chang Gung Memorial Hospital, No. 5, Fu-Hsing Street, Gueishan District, Taoyuan City, 33305, Taiwan.ORCID http://orcid.org/0000-0001-8414-595X
Ming-Shao TsaiCollege of Medicine, Chang Gung University, Taoyuan City, Taiwan.ORCID http://orcid.org/0000-0002-9314-5940
Li-Pang ChuangCollege of Medicine, Chang Gung University, Taoyuan City, Taiwan.ORCID http://orcid.org/0000-0001-5466-8995
Wan-Ni LinDepartment of Otorhinolaryngology, Head and Neck Surgery, Sleep Center, Linkou Medical Center, Chang Gung Memorial Hospital, No. 5, Fu-Hsing Street, Gueishan District, Taoyuan City, 33305, Taiwan.ORCID http://orcid.org/0000-0001-5782-8835
Li-Jen HsinDepartment of Otorhinolaryngology, Head and Neck Surgery, Sleep Center, Linkou Medical Center, Chang Gung Memorial Hospital, No. 5, Fu-Hsing Street, Gueishan District, Taoyuan City, 33305, Taiwan.ORCID http://orcid.org/0000-0001-9201-0270
Yi-Chieh LeeDepartment of Otorhinolaryngology - Head and Neck Surgery, New Taipei Municipal Tucheng Hospital, New Taipei City, Taiwan.ORCID http://orcid.org/0000-0002-6187-4102
Tuan-Jen FangDepartment of Otorhinolaryngology, Head and Neck Surgery, Sleep Center, Linkou Medical Center, Chang Gung Memorial Hospital, No. 5, Fu-Hsing Street, Gueishan District, Taoyuan City, 33305, Taiwan.ORCID http://orcid.org/0000-0002-7805-3458
Hsueh-Yu LiDepartment of Otorhinolaryngology, Head and Neck Surgery, Sleep Center, Linkou Medical Center, Chang Gung Memorial Hospital, No. 5, Fu-Hsing Street, Gueishan District, Taoyuan City, 33305, Taiwan. hyli38@cgmh.org.tw.ORCID http://orcid.org/0000-0002-9016-8098

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRapid eye movement-related obstructive sleep apnea (REM-OSA) is a physiological phenotype of OSA whose clinical significance and impact on surgical outcomes remain unclear. This study evaluated the prevalence, clinical characteristics, and predictive value of REM-OSA for palatal surgery outcomes.

methodsAdult patients with OSA intolerant of continuous positive airway pressure who underwent palatal surgery were retrospectively reviewed. REM-OSA was defined as a REM apnea-hypopnea index (AHI) at least twice the non-REM AHI. Surgical success was defined as a > 50% reduction in AHI and a postoperative AHI < 20 events/hour. Logistic regression was performed to identify predictors of surgical success.

resultsAmong 90 patients, 24 (26.7%) had REM-OSA. Compared with NREM-OSA, REM-OSA patients were younger (35.9 vs. 39.3 years, p = 0.043) and had lower baseline AHI (36.4 vs. 52.0 events/hour, p = 0.005). Although AHI reduction was similar between groups, REM-OSA showed a significantly higher surgical success rate (79.2% vs. 53.0%, p = 0.007). REM-OSA remained an independent predictor of surgical success after adjustment for age and baseline AHI (adjusted OR 5.44, 95% CI 1.41-21.00, p = 0.014).

conclusionsREM-OSA was associated with younger age and lower baseline disease severity. Although the absolute reduction in AHI following palatal surgery was comparable between groups, patients with REM-OSA achieved a significantly higher surgical success rate. These findings suggest that REM-OSA may serve as a clinically useful predictor of favorable outcomes following palatal surgery.

Indexed as

Clinical characteristicsOutcome predictorPhysiological phenotypePrevalenceRapid eye movement-related obstructive sleep apnea (REM-OSA)

Identifiers

PMID42760362

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.