Evidence map›Paper›PMID 42760355›Full record

ArticleAesthetic plastic surgery2026

Chemical Decompensation for Frontalis-Driven Multiple Eyelid Folds After Revision Double-Eyelid Surgery.

Hao Gong, Jiayu Qiang, Xiaolei Jin, Xiaoshuang Guo

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hao GongMaxillofacial Surgery Department of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 33 Ba-Da-Chu Road, Shi Jing Shan District, Beijing, 100144, People's Republic of China.
Jiayu QiangDepartment of Anorectal Surgery, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, People's Republic of China.
Xiaolei JinMaxillofacial Surgery Department of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 33 Ba-Da-Chu Road, Shi Jing Shan District, Beijing, 100144, People's Republic of China. zxyy16jxl@163.com.
Xiaoshuang GuoMaxillofacial Surgery Department of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 33 Ba-Da-Chu Road, Shi Jing Shan District, Beijing, 100144, People's Republic of China. guoxinpumc@psh.pumc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple eyelid folds after revision double-eyelid surgery are commonly attributed to structural factors. This single-patient report describes a possible contribution of acquired compensatory frontalis activation and a temporary intervention termed chemical decompensation.

methodsAA 28-year-old woman with unilateral multiple eyelid folds after revision surgery underwent brow-eyelid continuum assessment. After manual confirmation of adequate independent levator function, unilateral low-dose onabotulinumtoxinA (5 U) was administered above the affected brow. Evaluation included paired photographs, perceived-improvement ratings from five evaluators, and eyelid-opening measurements. Follow-up ultrasonography was performed 116 days after injection.

resultsAt one week, paired photographic review showed reduced multiple folding, with a mean visual analog scale perceived-improvement score of 7.3 ± 0.67 and no observed functional compromise. Follow-up ultrasonography showed findings consistent with a local adhesion/fixation point. The improvement suggests that dynamic frontalis traction contributed to the visible deformity, but does not independently confirm adhesion or quantify the relative dynamic and structural contributions.

conclusionChemical decompensation may provide temporary improvement during recovery while scar maturation and later reassessment proceed. The post-injection response offers supportive, case-specific information rather than a validated diagnostic test. This approach does not replace definitive revision when indicated. Prospective validation in larger cohorts is warranted. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

BlepharoplastyChemical decompensationFrontalis-driven compensationMultiple eyelid foldsRevision double-eyelid surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.