Evidence map›Paper›PMID 42760322›Full record

ArticleNature neuroscience2026

Serotonin neurons in the dorsal raphe control food-craving-like behavior during pregnancy in mice.

Qianru Zhao, Bing Feng, Vicky Dong, Lee How Lau, Hailan Liu, Meng Yu, Keqin Liang, Cindy Tran, Heidi Feng, Taylor Smiley and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Qianru Zhao *Pennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA.
Bing Feng *Pennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA.ORCID http://orcid.org/0000-0002-7403-8402
Vicky Dong *Pennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA.
Lee How LauSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.
Hailan LiuChildren's Nutrition Research Center, Texas Children's Research Institute, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Meng YuChildren's Nutrition Research Center, Texas Children's Research Institute, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Keqin LiangDepartment of Biological Chemistry, School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China.
Cindy TranPennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA.
Heidi FengPennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA.
Taylor SmileyPennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA.
Peiyu GaoPennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA.
Amy YanPennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA.
Hui YeSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.
Yuwei JiangDepartment of Physiology, The University of Illinois Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-5082-8012
Chunmei WangChildren's Nutrition Research Center, Texas Children's Research Institute, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA. Chunmei.Wang@bcm.edu.ORCID http://orcid.org/0000-0001-8104-6892
Pingwen XuDivision of Endocrinology, Department of Medicine, The University of Illinois Chicago, Chicago, IL, USA. pingwenx@uic.edu.ORCID http://orcid.org/0000-0001-9363-4114
Yanlin HePennington Biomedical Research Center, Brain Glycemic and Metabolism Control Department, Louisiana State University, Baton Rouge, LA, USA. Yanlin.He@pbrc.edu.ORCID http://orcid.org/0000-0002-5471-9016

Funding

Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI RONALD N COHEN · 2013 to 2026
$20.9M
Testosterone and estrogen signaling pathways in the medial amygdala interact to control energy homeostasisR01DK123098 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI XU, PINGWEN · 2020 to 2024
$2.5M
ESTROGEN-INDUCIBLE PNNS ENHANCE EXCITATORY SYNAPTIC STRENGTH ONTO GABA NEURONS IN THE MEPD TO PREVENT OBESITY AND METABOLIC DYSREGULATIONR01DK136627 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Chunmei Wang · 2023 to 2026
$1.8M
Doral raphe 5-HT neurons mediating estrogenic regulation of binge drinkingR01AA030880 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Pingwen Xu · 2024 to 2026
$1.7M
American Diabetes Association (ADA) 1-17-PDF-138NSF | BIO | Division of Biological Infrastructure (DBI) NSF(2024)-SURE-313United States Department of Agriculture | Agricultural Research Service (USDA Agricultural Research Service) 58-3092-5-008U.S. Department of Defense (United States Department of Defense) W81XWH-20-1-0075U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) P30 DK020595U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R01 DK123098U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R01DK136627U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) R01 AA030880
6 · The paper itself

Abstract

During pregnancy, physiological changes can alter food intake behaviors. However, the underlying neural mechanisms remain unclear. Here we show that female mice exhibit food-craving-like behavior during pregnancy, mirroring many patterns described in humans. We show that 5-HT

Identifiers

PMID42760322

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.