Evidence map›Paper›PMID 42758827›Full record

ArticleScience advances2026

Ubiquitin receptor-mediated, ubiquitin-independent targeted protein degradation via 26

Seh Hoon Park, Yejin Jang, Soo-Yeon Lee, Eunseo Kim, Dawon Jeong, Insuk Byun, Jiseong Kim, Jisoo Yang, Chang-Han Lee, Dohyun Han and 2 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Seh Hoon ParkDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0009-0005-1185-9114
Yejin JangDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0009-0007-4833-2679
Soo-Yeon LeeDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do 14662, Korea.ORCID 0009-0003-2209-2786
Eunseo KimDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.
Dawon JeongDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0009-0008-9791-5907
Insuk ByunDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0003-2102-5971
Jiseong KimDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0009-0000-7310-452X
Jisoo YangDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.ORCID 0009-0002-1505-7619
Chang-Han LeeDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.ORCID 0000-0002-7156-4423
Dohyun HanProteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.ORCID 0000-0002-0841-1598
Jae-Hwan NamDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Gyeonggi-do 14662, Korea.ORCID 0000-0001-7555-1091
Min Jae LeeDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0002-3252-6467

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 26

Indexed as

Proteasome Endopeptidase ComplexProteolysisUbiquitinAnimalsHumansMiceProteolysis Targeting ChimeraProto-Oncogene Proteins c-fosUbiquitinationATP dependent 26S proteaseProteasome Endopeptidase ComplexProteolysis Targeting ChimeraProto-Oncogene Proteins c-fosUbiquitin

Identifiers

PMID42758827
PMCPMC13588176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.