ArticleEuropean stroke journal2026
Initial magnetic resonance imaging/magnetic resonance angiography may miss intracranial artery dissection in young adults with stroke: the role of subsequent imaging.
Article in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
introductionIntracranial artery dissection (IAD) is an important cause of ischaemic stroke in young adults; however, its diagnosis at initial presentation remains challenging. We aimed to determine how often initial magnetic resonance imaging (MRI)/magnetic resonance angiography (MRA) and subsequent imaging identified IAD, and to clarify the timing of IAD diagnosis.
methodsWe performed a secondary analysis of a prospective, multicentre registry of 275 adults aged 18-50 years admitted with acute ischaemic stroke within 14 days of onset. All patients underwent MRI/MRA at admission, followed by scheduled follow-up MRI/MRA 7 days later. Vessel wall MRI (VW-MRI), digital subtraction angiography (DSA) and computed tomography angiography (CTA) were performed when clinically indicated. The proportion of patients in whom each examination identified IAD and the time to diagnosis were assessed.
resultsIAD was diagnosed in 53 patients. Initial MRI/MRA identified IAD in only 9 (17%; 95% CI, 8-30). The median time to diagnosis was 5 days after admission; 77% had been diagnosed by Day 7, and the latest diagnosis was made on Day 35. Among patients who underwent each examination, the observed diagnostic yield was 38 of 45 for VW-MRI (84%; 95% CI, 71-94), 41 of 53 for follow-up MRI/MRA (77%; 95% CI, 64-88), 15 of 30 for DSA (50%; 95% CI, 31-69) and 7 of 34 for CTA (21%; 95% CI, 9-38).
conclusionAmong young adults with ischaemic stroke who ultimately met the imaging criteria for IAD, initial MRI/MRA alone was insufficient to establish the diagnosis in most cases. Repeated and multimodal imaging contributed to the diagnosis of IAD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.