Evidence map›Paper›PMID 42758326›Full record

ArticleZeitschrift fur Rheumatologie2026

[Rheuma-VOR-Health economic evaluation of early rheumatological diagnosis : Summary of the G-BA report].

Juliana Rachel Hoeper, Matthias Dreher, Julian Maximilian Kohl, Marlon Grodd, Johanna Callhoff, Andreas Schwarting, Jan Zeidler

Abstract readEnglish Abstract
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In one paragraph

Article in Zeitschrift fur Rheumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juliana Rachel HoeperCenter for Health Economics Research Hannover (CHERH), Leibniz Universität Hannover, Königsworther Platz 1, 30167, Hannover, Deutschland.
Matthias DreherSchwerpunkt Rheumatologie und klinische Immunologie, Universitätsmedizin Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland. Matthias.Dreher@unimedizin-mainz.de.ORCID https://orcid.org/0000-0002-9171-3780
Julian Maximilian KohlSchwerpunkt Rheumatologie und klinische Immunologie, Universitätsmedizin Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland.
Marlon GroddInstitut für Medizinische Biometrie und Statistik, Universitätsklinikum Freiburg, Freiburg, Deutschland.
Johanna CallhoffProgrammbereich Epidemiologie, Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Deutschland.ORCID https://orcid.org/0000-0002-3923-2728
Andreas SchwartingSchwerpunkt Rheumatologie und klinische Immunologie, Universitätsmedizin Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland.ORCID https://orcid.org/0000-0002-0566-598X
Jan ZeidlerCenter for Health Economics Research Hannover (CHERH), Leibniz Universität Hannover, Königsworther Platz 1, 30167, Hannover, Deutschland. jz@cherh.de.ORCID https://orcid.org/0000-0002-0104-2267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheuma-VOR was initiated to reduce long waiting times for specialist diagnosis and guideline-based therapy initiation in rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA).

methodsRheuma-VOR is a prospective, nonrandomized, multicenter network study with an embedded health economic evaluation. Using a quasi-experimental cohort design and propensity score matching, the intervention group (Rheuma-VOR) was compared with standard care (national database). Direct costs (medications, hospital, and rehabilitation) and indirect costs (productivity losses) were analyzed from a societal perspective.

resultsRheuma-VOR achieved total savings of € 3.84 million versus standard care, mainly due to fewer hospitalizations (-€ 1.15 million), reduced drug costs (-€ 2.03 million), and improved work capacity (-€ 0.70 million indirect costs). Fewer biologics were prescribed (2.4 % vs. 11.8 %). The model demonstrated a dominant cost-effectiveness profile: similar or better health-related quality of life at lower total costs (Rheuma-VOR: € 2,445.17/patient, 95 % confidence interval [CI] € 1,955.79-€ 3,041.50; standard care: € 3,107.33/patient, 95% CI € 1,958.28-€ 3,997.62). Annual coordination center costs (€ 272.35/patient) were fully offset by savings.

conclusionStructured, cross-sectoral care models like Rheuma-VOR reduce diagnostic delays, optimize resource use, and are economically sustainable. Long-term benefits include additional savings through prevention of irreversible damage.

Indexed as

Cost-effectiveness analysisDirect and indirect healthcare costsEarly diagnosisRheumatic diseasesRheuma-VOR

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.