Evidence map›Paper›PMID 42758258›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

High-density mapping of his-ventricular intervals: impact of recording site and sex-specific differences.

Teodor Serban, Jeanne du Fay de Lavallaz, Sven Knecht, David Spreen, Behnam Subin, Reto Stump, Philipp Krisai, Nicolas Schärli, Beat Schär, Felix Mahfoud and 3 more

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Teodor SerbanUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Jeanne du Fay de LavallazUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Sven KnechtUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
David SpreenUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Behnam SubinUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Reto StumpUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Philipp KrisaiUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Nicolas SchärliUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Beat SchärUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Felix MahfoudUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Christian SticherlingUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Michael KühneUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Patrick BadertscherUniversity Hospital of Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland. patrick.badertscher@usb.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate assessment of the His-ventricular (HV) interval is essential to diagnosing infranodal conduction disease, but the influence of recording site and sex on HV values is not well defined.

objectiveTo evaluate the impact of measurement location and sex on HV interval values using high-density (HD) mapping catheters in patients undergoing atrial fibrillation (AF) ablation.

methodsWe prospectively studied patients in sinus rhythm undergoing AF ablation. HV intervals were measured with a decapolar catheter and a HD mapping catheter at the end of the procedure. HD-based HV intervals were classified as proximal (HV

resultsA total of 67 patients (mean age 64 ± 10 years, 33%women) were evaluated. The clinical HV interval was 45 ± 9 ms and shorter in women (40 ms vs. 47 ms, p < 0.001). HV

conclusionHV interval measurements vary significantly by recording site and sex. Proximal measurements reveal longer HV intervals and detect more conduction delays, while women have systematically shorter HV intervals. Anatomical precision and sex-specific interpretation are important for accurate diagnosis of infranodal conduction delay.

Indexed as

Atrial FibrillationBody Surface Potential MappingBundle of HisCatheter AblationElectrocardiographyFemaleHeart Conduction SystemHumansMaleMiddle AgedProspective StudiesReproducibility of ResultsSensitivity and SpecificitySex FactorsHis Bundle ElectrogramHis CloudHis-Ventricle Interval

Identifiers

PMID42758258
PMCPMC13645979

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