ArticleMolecular biomedicine2026
Induction of transferrin receptor 1-mediated ferroptosis by ultrasound-triggered microbubble destruction sensitizes glioblastoma to radiotherapy.
Article in Molecular biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Ultrasound-triggered microbubble destruction (UTMD), a non-invasive technique, has been proposed as a promising means of improving the efficacy of radiotherapy against glioblastoma (GBM); however, the underlying mechanisms remain to be fully clarified. Here, UTMD was shown to induce ferroptosis, an iron-dependent form of regulated cell death, in ionizing radiation (IR)-treated GL261 and 1016B cells, as evidenced by decreased cell viability, glutathione, and glutathione peroxidase 4 levels, and increased total reactive oxygen species (ROS), lipid ROS, iron/Fe
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