Evidence map›Paper›PMID 42758174›Full record

ArticleEuropean journal of translational myology2026

Patient-specific 3D-printed implants for reconstruction of elbow nonunion with bone defects: a case report and technical note.

Giacomo Mazzei, Jose Carlos Orihuela, Ignacio Maria Silva Rossi, Alberto Alvarez Jimenez, Luis Bahillo O'Mahoney, Francisco Castellano Torres, Giuseppe Rovere, Luigi Meccariello

Abstract read
In one paragraph

Article in European journal of translational myology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giacomo MazzeiDepartment of Orthopedics and Traumatology, HUGCDN, Hospital Universitario Dr Negrin, Las Palmas.
Jose Carlos OrihuelaDepartment of Orthopedics and Traumatology, HUGCDN, Hospital Universitario Dr Negrin, Las Palmas.
Ignacio Maria Silva RossiDepartment of Orthopedics and Traumatology, HUGCDN, Hospital Universitario Dr Negrin, Las Palmas.
Alberto Alvarez JimenezDepartment of Orthopedics and Traumatology, HUGCDN, Hospital Universitario Dr Negrin, Las Palmas.
Luis Bahillo O'MahoneyDepartment of Orthopedics and Traumatology, HUGCDN, Hospital Universitario Dr Negrin, Las Palmas.
Francisco Castellano TorresDepartment of Orthopedics and Traumatology, HUGCDN, Hospital Universitario Dr Negrin, Las Palmas.
Giuseppe RovereDepartment of Clinical Science and Translational Medicine, Section of Orthopaedics and Traumatology, University of Rome "Tor Vergata", Rome.
Luigi MeccarielloDepartment of Orthopedics and Traumatology, AORN San Pio Hospital, Benevento.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distal humeral nonunion associated with extensive bone loss remains one of the most challenging reconstructive conditions in upper-extremity surgery. We present a technically demanding case treated using a patient-specific 3D-printed implant and discuss its potential advantages compared with alternative reconstructive strategies. This case report describes the management of a 59-year-old woman presenting with a hypertrophic distal humeral shaft nonunion three years after intramedullary nailing. Preoperative evaluation included bilateral Computed Tomography (CT) using a dedicated low-artifact acquisition protocol to enable contralateral humeral mirroring, three-dimensional virtual planning, and the design of a patient-specific implant. A custom-made Ti6Al4V implant featuring a cemented proximal stem, a porous metaphyseal interface, and a dual-flange distal fixation platform was manufactured based on the preoperative planning. Reconstruction was performed through a posterior approach with olecranon osteotomy using patient-specific cutting guides. Clinical and radiographic outcomes were prospectively assessed at 1, 3, 6, and 12 months postoperatively. Progressive improvements were observed in elbow motion, MEPS, TCI, and sleep quality (PSQI). By 12 months, the patient achieved near-complete ROM and excellent clinical scores, with radiographs showing full union and stable alignment. At 1 year, however, a fall resulted in proximal stem mobilization, while the distal fixation and porous interface remained stable. This case demonstrates that patient-specific reconstruction can achieve accurate anatomical restoration, stable fixation, and excellent functional recovery in selected patients with complex distal humeral nonunion and bone loss. It also highlights the potential advantages of customized implants, while emphasizing the importance of meticulous preoperative planning, complete implant fixation, and appropriate postoperative protection to minimize the risk of late mechanical failure. Although the present findings are encouraging, further clinical studies are required to establish the long-term effectiveness and broader applicability of this reconstructive strategy.

Indexed as

3D printingcomputer-assistedcustom-madeelbowhumerusNonunion

Identifiers

PMID42758174
PMCPMC13688312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.