Evidence map›Paper›PMID 42757757›Full record

ArticleJournal of global health2026

Frontline healthcare worker barriers impacting tuberculosis service demand and access in high burden settings: a scoping review.

Samyra R Cox, Colleen F Hanrahan, Aye Hnin Moe, Kate Shearer, Canice Christian, Sejal Sethi, Mollie Hudson, Manami Ueshima, Kalee Singh, Jane Dawson and 6 more

Abstract readScoping Review
In one paragraph

Article in Journal of global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Samyra R Cox *Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Colleen F Hanrahan *Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Aye Hnin MoeCenter for Tuberculosis Research, Johns Hopkins University, Baltimore, USA.
Kate ShearerCenter for Tuberculosis Research, Johns Hopkins University, Baltimore, USA.
Canice ChristianCenter for Tuberculosis, University of California San Francisco, San Francisco, USA.
Sejal SethiJohns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Mollie HudsonCenter for Tuberculosis, University of California San Francisco, San Francisco, USA.
Manami UeshimaJohns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Kalee SinghCenter for Tuberculosis, University of California San Francisco, San Francisco, USA.
Jane DawsonJohns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Ketholelie AngamiAccess to Rights and Knowledge Foundation, Kohima, Nagaland, India.
Nyiko KubaiAfrocab Treatment Access Partnership, Lusaka, Zambia.
Mangala NamasivayamAPCASO, Bangkok, Thailand.
Priya SheteCenter for Tuberculosis, University of California San Francisco, San Francisco, USA.
Jonathan E GolubJohns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Andrew D KerkhoffCenter for Tuberculosis, University of California San Francisco, San Francisco, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Extensive literature exists on health-seeking behaviour and barriers related to the uptake of tuberculosis (TB)-related services in high TB burden settings. However, prior reviews have focused on patient- and health facility/systems-level barriers to TB-related care. In this scoping review, we aimed to synthesise frontline healthcare worker (FLHCW)-related barriers that limit individuals' demand for, access to, and retention in TB services. Methods: We searched PubMed for studies describing FLHCW-related barriers that impact demand for and/or access to TB services (preventive treatment, active case finding, diagnosis and treatment initiation, treatment completion, and post-TB care). We included studies that were published between 2010 and 2025 in English, and that reported on original research findings from the World Health Organization lists of high TB burden countries. Two reviewers independently conducted title and abstract screening, and full-text review. We narratively summarised barriers by theme and applied the Capability, Opportunity, Motivation-Behavior (COM-B) framework to facilitate interpretation. Results: We screened a total of 5,306 records, and included 189 studies, most of which were from India, South Africa, and Ethiopia. Among the included studies, most reported barriers were for doctors (n = 101, 53%) and nurses (n = 82, 43%). Studies identified FLHCW-related barriers at every step of the care cascade except for post-TB care. Knowledge and skill gaps leading to missed opportunities to engage or retain individuals in care were the most frequent barriers identified (n = 128 studies). Other major themes included provider-patient communication, discrimination and stigma from FLHCWs, and motivation to provide quality TB clinical care. Mapping barriers onto COM-B identified actionable targets for strategies to improve TB care. Conclusions: FLHCW-related barriers to TB care are pervasive and multifaceted, affecting the care cascade from prevention to diagnosis to treatment initiation and completion. Addressing these barriers will require multi-component implementation strategies that are context-specific and designed to empower FLHCWs as drivers of care.

Indexed as

Frontline WorkersHealth PersonnelHealth Services AccessibilityHealth Services Needs and DemandTuberculosisHumanshealth personnelhealth services accessibilityhealth services researchreviewtuberculosis

Identifiers

PMID42757757
PMCPMC13587593

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.