Evidence map›Paper›PMID 42757480›Full record

ArticleInternational journal of molecular medicine2026

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons

Tan-Zhen Xu, Xiao-Yan Shen, Ling-Ling Sun, Ya-Li Chen, Bi-Qiong Zhang, Da-Ke Huang, Wei-Zu Li

Abstract readExpression of Concern
In one paragraph

Article in International journal of molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Tan-Zhen XuDepartment of Pharmacology, Key Laboratory of Anti‑inflammatory and Immunopharmacology, Ministry of Education, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Xiao-Yan ShenDepartment of Pharmacology, Key Laboratory of Anti‑inflammatory and Immunopharmacology, Ministry of Education, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Ling-Ling SunDepartment of Pharmacology, Key Laboratory of Anti‑inflammatory and Immunopharmacology, Ministry of Education, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Ya-Li ChenDepartment of Pharmacology, Key Laboratory of Anti‑inflammatory and Immunopharmacology, Ministry of Education, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Bi-Qiong ZhangDepartment of Pharmacology, Key Laboratory of Anti‑inflammatory and Immunopharmacology, Ministry of Education, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Da-Ke HuangSynthetic Laboratory of Basic Medicine College, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Wei-Zu LiDepartment of Pharmacology, Key Laboratory of Anti‑inflammatory and Immunopharmacology, Ministry of Education, Anhui Medical University, Hefei, Anhui 230032, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by an interested reader that an unsuitable antibody may have been used as a part of the western blot analysis shown in Fig. 3A on p. 720. The anti‑β‑galactosidase antibody (cat. no. ab9361; Abcam) that was employed, which is specific for the

Indexed as

Adaptor Proteins, Signal TransducingGinsenosidesHippocampusHydrogen PeroxideInflammasomesNeuronsSignal TransductionAnimalsHumansAdaptor Proteins, Signal Transducingginsenoside Rg1GinsenosidesHydrogen PeroxideInflammasomesginsenoside Rg1hippocampal neuronsNADPH oxidase 2nucleotide-binding oligomerisation domain-like receptor protein 1 inflammasomereactive oxygen species oxidative stress

Identifiers

PMID42757480
PMCPMC13600328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.